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- W1981845717 abstract "ABSTRACT The purpose of the present study was to clarify the hypothalamic action of leptin on the secretion of luteinizing hormone (LH) and growth hormone (GH) in cattle. Intracerebroventricular (the third ventricle) injections of leptin were given to fully fed castrated Holstein calves. Blood samples were collected at 10‐min intervals for 60 min after injection and 20‐min intervals for 60 min before injection and for 60–180 min after injection through an indwelling catheter in the external jugular vein. Plasma LH and GH levels were examined by homologous radioimmunoassay. The administration of 10 µg of leptin stimulated a significant ( P < 0.05) release of GH but not LH. Average GH levels began to rise after 30 min and were significantly increased at 40, 50 and 60 min after the injection, compared with the respective control values ( P < 0.05). The present result suggests that leptin may act partly on the hypothalamus to stimulate the release of GH in castrated calves." @default.
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- W1981845717 date "2006-03-30" @default.
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- W1981845717 title "Effects of intracerebroventricular injections of leptin on the release of luteinizing hormone and growth hormone in castrated calves" @default.
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- W1981845717 doi "https://doi.org/10.1111/j.1740-0929.2006.00337.x" @default.
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