Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981856462> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W1981856462 abstract "of invading bacbria by neutrophilic polymorphonuclear leukocytes (PMN) is an important aspect of pulmonary host defense.l Opsonins play a key role in the process by facilitating uptake of bacteria by PMN. Opsonic substances m serum include heat-stable components such as specific antibody, which usually develops later in the course of infection, and heat-labile factors, like those produced rapidly by activation of the complement cascade.¶ Fdlowing engulfment of opsonized bacteria, PMN consume oxygen, undergo a series of metabolic reactions, and produce highly reactive oxygen intermediates.a.4 These oxygen byproducts are necessary for optimal killing of ingested bacteria by PMN.' In association with production of these oxygen intermediates, PMN generate chemiluminescence. This light can be measured in a scintillation counter and used to accurately quantitate the metabolic reactions of PMN to engulfment of bacte~ia.&-~ The nature of the requirements for the complex processes by which PMN pick up and kill bacteria and produce chemiluminescence remain poorly d&d8*@ In the present investigation, we evaluated the effect of a selective absence of the second component of camplement (C2) on the uptake of bacteria by PMN, using both a standard assay of PMN bactericidal activity and an assay of the quantitative chemiluminemmce response of PMN stimulated by bacteria.@*7J0 The patient we studied had a complete selective absence of C2 by radial immun- or immundectrophoresis analy" @default.
- W1981856462 created "2016-06-24" @default.
- W1981856462 creator A5002526678 @default.
- W1981856462 creator A5042933114 @default.
- W1981856462 creator A5044609979 @default.
- W1981856462 creator A5057139432 @default.
- W1981856462 date "1979-02-01" @default.
- W1981856462 modified "2023-09-25" @default.
- W1981856462 title "Effect of C2-Deficiency on the Bactericidal Activity and Chemiluminescence Responses of Human Neutrophils in vitro" @default.
- W1981856462 cites W1660535336 @default.
- W1981856462 cites W1915832820 @default.
- W1981856462 cites W1968034904 @default.
- W1981856462 cites W2012459412 @default.
- W1981856462 cites W2023122744 @default.
- W1981856462 cites W2050024502 @default.
- W1981856462 cites W2063670271 @default.
- W1981856462 cites W2087822696 @default.
- W1981856462 cites W2418827582 @default.
- W1981856462 cites W2418974924 @default.
- W1981856462 doi "https://doi.org/10.1378/chest.75.2_supplement.252" @default.
- W1981856462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/374014" @default.
- W1981856462 hasPublicationYear "1979" @default.
- W1981856462 type Work @default.
- W1981856462 sameAs 1981856462 @default.
- W1981856462 citedByCount "3" @default.
- W1981856462 crossrefType "journal-article" @default.
- W1981856462 hasAuthorship W1981856462A5002526678 @default.
- W1981856462 hasAuthorship W1981856462A5042933114 @default.
- W1981856462 hasAuthorship W1981856462A5044609979 @default.
- W1981856462 hasAuthorship W1981856462A5057139432 @default.
- W1981856462 hasConcept C111684460 @default.
- W1981856462 hasConcept C145802702 @default.
- W1981856462 hasConcept C159654299 @default.
- W1981856462 hasConcept C160448771 @default.
- W1981856462 hasConcept C168507396 @default.
- W1981856462 hasConcept C178790620 @default.
- W1981856462 hasConcept C185592680 @default.
- W1981856462 hasConcept C198677920 @default.
- W1981856462 hasConcept C202751555 @default.
- W1981856462 hasConcept C203014093 @default.
- W1981856462 hasConcept C2778870864 @default.
- W1981856462 hasConcept C43617362 @default.
- W1981856462 hasConcept C48349386 @default.
- W1981856462 hasConcept C523546767 @default.
- W1981856462 hasConcept C540031477 @default.
- W1981856462 hasConcept C54355233 @default.
- W1981856462 hasConcept C55493867 @default.
- W1981856462 hasConcept C86803240 @default.
- W1981856462 hasConcept C89372155 @default.
- W1981856462 hasConcept C89423630 @default.
- W1981856462 hasConcept C99971728 @default.
- W1981856462 hasConceptScore W1981856462C111684460 @default.
- W1981856462 hasConceptScore W1981856462C145802702 @default.
- W1981856462 hasConceptScore W1981856462C159654299 @default.
- W1981856462 hasConceptScore W1981856462C160448771 @default.
- W1981856462 hasConceptScore W1981856462C168507396 @default.
- W1981856462 hasConceptScore W1981856462C178790620 @default.
- W1981856462 hasConceptScore W1981856462C185592680 @default.
- W1981856462 hasConceptScore W1981856462C198677920 @default.
- W1981856462 hasConceptScore W1981856462C202751555 @default.
- W1981856462 hasConceptScore W1981856462C203014093 @default.
- W1981856462 hasConceptScore W1981856462C2778870864 @default.
- W1981856462 hasConceptScore W1981856462C43617362 @default.
- W1981856462 hasConceptScore W1981856462C48349386 @default.
- W1981856462 hasConceptScore W1981856462C523546767 @default.
- W1981856462 hasConceptScore W1981856462C540031477 @default.
- W1981856462 hasConceptScore W1981856462C54355233 @default.
- W1981856462 hasConceptScore W1981856462C55493867 @default.
- W1981856462 hasConceptScore W1981856462C86803240 @default.
- W1981856462 hasConceptScore W1981856462C89372155 @default.
- W1981856462 hasConceptScore W1981856462C89423630 @default.
- W1981856462 hasConceptScore W1981856462C99971728 @default.
- W1981856462 hasLocation W19818564621 @default.
- W1981856462 hasLocation W19818564622 @default.
- W1981856462 hasOpenAccess W1981856462 @default.
- W1981856462 hasPrimaryLocation W19818564621 @default.
- W1981856462 hasRelatedWork W1977558870 @default.
- W1981856462 hasRelatedWork W1992393617 @default.
- W1981856462 hasRelatedWork W2010940838 @default.
- W1981856462 hasRelatedWork W2024431897 @default.
- W1981856462 hasRelatedWork W2026378555 @default.
- W1981856462 hasRelatedWork W2047802418 @default.
- W1981856462 hasRelatedWork W2062794342 @default.
- W1981856462 hasRelatedWork W2276761526 @default.
- W1981856462 hasRelatedWork W1693763825 @default.
- W1981856462 hasRelatedWork W2478545346 @default.
- W1981856462 isParatext "false" @default.
- W1981856462 isRetracted "false" @default.
- W1981856462 magId "1981856462" @default.
- W1981856462 workType "article" @default.