FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981860093> ?p ?o ?g. }

• W1981860093 endingPage "194" @default.
• W1981860093 startingPage "189" @default.
• W1981860093 abstract "TNF‐α, generated during the systemic inflammatory response, triggers a wide range of biological activities that mediate the neurologic manifestations associated with cancer and infection. Since this cytokine regulates ion channels in vitro (especially Kv1.3 and Kir2.1), we aimed to study Kv1.3 and Kir2.1 expression in brain in response to in vivo systemic inflammation. Cancer‐induced cachexia and LPS administration increased plasma TNF‐α. Kv1.3 and Kir2.1 expression was impaired in brain during cancer cachexia. However, LPS treatment induced Kv1.3 and downregulated Kir2.1 expression, and TNF‐α administration mimicked these results. Experiments using TNF‐α double receptor knockout mice demonstrated that the systemic inflammatory response mediates K + channel regulation in brain via TNF‐α‐dependent and ‐independent redundant pathways. In summary, distinct neurological alterations associated with systemic inflammation may result from the interaction of various cytokine pathways tuning ion channel expression in response to neurophysiological and neuroimmunological processes." @default.
• W1981860093 created "2016-06-24" @default.
• W1981860093 creator A5005897976 @default.
• W1981860093 creator A5036533821 @default.
• W1981860093 creator A5038194778 @default.
• W1981860093 creator A5048204665 @default.
• W1981860093 creator A5067065508 @default.
• W1981860093 creator A5067995365 @default.
• W1981860093 creator A5085196030 @default.
• W1981860093 date "2004-07-22" @default.
• W1981860093 modified "2023-10-17" @default.
• W1981860093 title "The systemic inflammatory response is involved in the regulation of K⁺channel expression in brain via TNF-α-dependent and -independent pathways" @default.
• W1981860093 cites W1487109629 @default.
• W1981860093 cites W1668853735 @default.
• W1981860093 cites W1969685127 @default.
• W1981860093 cites W1976845082 @default.
• W1981860093 cites W1994203972 @default.
• W1981860093 cites W2011094963 @default.
• W1981860093 cites W2011846994 @default.
• W1981860093 cites W2016923704 @default.
• W1981860093 cites W2019067219 @default.
• W1981860093 cites W2019386006 @default.
• W1981860093 cites W2019649093 @default.
• W1981860093 cites W2024476573 @default.
• W1981860093 cites W2025392129 @default.
• W1981860093 cites W2026836401 @default.
• W1981860093 cites W2027900036 @default.
• W1981860093 cites W2034799298 @default.
• W1981860093 cites W2036354440 @default.
• W1981860093 cites W2036809235 @default.
• W1981860093 cites W2040096338 @default.
• W1981860093 cites W2040368687 @default.
• W1981860093 cites W2041138100 @default.
• W1981860093 cites W2044454983 @default.
• W1981860093 cites W2051405987 @default.
• W1981860093 cites W2052521148 @default.
• W1981860093 cites W2054415514 @default.
• W1981860093 cites W2071885164 @default.
• W1981860093 cites W2075532969 @default.
• W1981860093 cites W2077012020 @default.
• W1981860093 cites W2088335573 @default.
• W1981860093 cites W2091680030 @default.
• W1981860093 cites W2093202108 @default.
• W1981860093 cites W2096030406 @default.
• W1981860093 cites W2101574654 @default.
• W1981860093 cites W2109403460 @default.
• W1981860093 cites W2115802065 @default.
• W1981860093 cites W2120162713 @default.
• W1981860093 cites W2141844501 @default.
• W1981860093 cites W2189016339 @default.
• W1981860093 cites W2193797780 @default.
• W1981860093 cites W298305597 @default.
• W1981860093 cites W4237137145 @default.
• W1981860093 cites W4313635400 @default.
• W1981860093 doi "https://doi.org/10.1016/j.febslet.2004.07.030" @default.
• W1981860093 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15304346" @default.
• W1981860093 hasPublicationYear "2004" @default.
• W1981860093 type Work @default.
• W1981860093 sameAs 1981860093 @default.
• W1981860093 citedByCount "29" @default.
• W1981860093 countsByYear W19818600932012 @default.
• W1981860093 countsByYear W19818600932014 @default.
• W1981860093 countsByYear W19818600932015 @default.
• W1981860093 countsByYear W19818600932017 @default.
• W1981860093 countsByYear W19818600932018 @default.
• W1981860093 countsByYear W19818600932019 @default.
• W1981860093 countsByYear W19818600932020 @default.
• W1981860093 countsByYear W19818600932022 @default.
• W1981860093 crossrefType "journal-article" @default.
• W1981860093 hasAuthorship W1981860093A5005897976 @default.
• W1981860093 hasAuthorship W1981860093A5036533821 @default.
• W1981860093 hasAuthorship W1981860093A5038194778 @default.
• W1981860093 hasAuthorship W1981860093A5048204665 @default.
• W1981860093 hasAuthorship W1981860093A5067065508 @default.
• W1981860093 hasAuthorship W1981860093A5067995365 @default.
• W1981860093 hasAuthorship W1981860093A5085196030 @default.
• W1981860093 hasBestOaLocation W19818600931 @default.
• W1981860093 hasConcept C121608353 @default.
• W1981860093 hasConcept C126322002 @default.
• W1981860093 hasConcept C150903083 @default.
• W1981860093 hasConcept C169760540 @default.
• W1981860093 hasConcept C170493617 @default.
• W1981860093 hasConcept C17991360 @default.
• W1981860093 hasConcept C182704531 @default.
• W1981860093 hasConcept C203014093 @default.
• W1981860093 hasConcept C207001950 @default.
• W1981860093 hasConcept C25498285 @default.
• W1981860093 hasConcept C25938499 @default.
• W1981860093 hasConcept C2776252253 @default.
• W1981860093 hasConcept C2776914184 @default.
• W1981860093 hasConcept C2777704314 @default.
• W1981860093 hasConcept C2778690821 @default.
• W1981860093 hasConcept C502942594 @default.
• W1981860093 hasConcept C62478195 @default.
• W1981860093 hasConcept C71924100 @default.
• W1981860093 hasConcept C86803240 @default.
• W1981860093 hasConcept C95444343 @default.
• W1981860093 hasConcept C98274493 @default.

• next