FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981985293> ?p ?o ?g. }

• W1981985293 endingPage "1326" @default.
• W1981985293 startingPage "1322" @default.
• W1981985293 abstract "This naturalistic study explored long-term effectiveness of adjunctive lamotrigine therapy for bipolar II depression. We analyzed prospective data from 109 lamotrigine-treated outpatients with bipolar II depression inadequately responsive to mood stabilizers. Lamotrigine was added to prior treatment in a naturalistic fashion. Changes in depression severity were prospectively monitored for up to 52 weeks using a prospective mood chart and the Clinical Global Impressions-Bipolar Version-Severity (CGI-BP-S). Time to lamotrigine discontinuation during 52-week period was calculated using the Kaplan-Meier estimate. A significant reduction in the CGI-BP-S depression score was observed between baseline and week 52 with a large effect size. The discontinuation rates were 44.0% and 50.5% for the total sample and 14.3% and 22.9% for responders at 24 weeks and 52 weeks, respectively. A higher number of prior hospitalizations for depression and a history of attempted suicide were associated with poor response to adjunctive lamotrigine treatment. Sustained benefits of an open-label lamotrigine add-on were indicated in patients with bipolar II depression. Adjunctive usage of lamotrigine was safe and generally well-tolerated. The potential benefit of adjunctive lamotrigine treatment was suggested in patients with bipolar II disorder suffering from depressive symptoms. Large-scale controlled studies are needed to confirm the effectiveness of adjunctive lamotrigine therapy for bipolar II depression." @default.
• W1981985293 created "2016-06-24" @default.
• W1981985293 creator A5005906334 @default.
• W1981985293 creator A5014695714 @default.
• W1981985293 creator A5020796809 @default.
• W1981985293 creator A5032091947 @default.
• W1981985293 date "2010-10-01" @default.
• W1981985293 modified "2023-10-02" @default.
• W1981985293 title "Adjunctive lamotrigine therapy for patients with bipolar II depression partially responsive to mood stabilizers" @default.
• W1981985293 cites W1964736667 @default.
• W1981985293 cites W1969010498 @default.
• W1981985293 cites W1977252830 @default.
• W1981985293 cites W1977674187 @default.
• W1981985293 cites W1978476616 @default.
• W1981985293 cites W1979589308 @default.
• W1981985293 cites W1991947158 @default.
• W1981985293 cites W1997191446 @default.
• W1981985293 cites W2005291821 @default.
• W1981985293 cites W2014062271 @default.
• W1981985293 cites W2017624254 @default.
• W1981985293 cites W2018575914 @default.
• W1981985293 cites W2021811222 @default.
• W1981985293 cites W2027375549 @default.
• W1981985293 cites W2034268588 @default.
• W1981985293 cites W2040553809 @default.
• W1981985293 cites W2057170051 @default.
• W1981985293 cites W2060687625 @default.
• W1981985293 cites W2061070907 @default.
• W1981985293 cites W2066364574 @default.
• W1981985293 cites W2084399232 @default.
• W1981985293 cites W2086074106 @default.
• W1981985293 cites W2109545626 @default.
• W1981985293 cites W2119349901 @default.
• W1981985293 cites W2120756984 @default.
• W1981985293 cites W2121009723 @default.
• W1981985293 cites W2128309600 @default.
• W1981985293 cites W2139035213 @default.
• W1981985293 cites W2147363529 @default.
• W1981985293 cites W2220387563 @default.
• W1981985293 cites W2917844777 @default.
• W1981985293 cites W4237575907 @default.
• W1981985293 doi "https://doi.org/10.1016/j.pnpbp.2010.07.020" @default.
• W1981985293 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20673782" @default.
• W1981985293 hasPublicationYear "2010" @default.
• W1981985293 type Work @default.
• W1981985293 sameAs 1981985293 @default.
• W1981985293 citedByCount "14" @default.
• W1981985293 countsByYear W19819852932012 @default.
• W1981985293 countsByYear W19819852932013 @default.
• W1981985293 countsByYear W19819852932015 @default.
• W1981985293 countsByYear W19819852932017 @default.
• W1981985293 countsByYear W19819852932018 @default.
• W1981985293 countsByYear W19819852932020 @default.
• W1981985293 countsByYear W19819852932021 @default.
• W1981985293 countsByYear W19819852932022 @default.
• W1981985293 countsByYear W19819852932023 @default.
• W1981985293 crossrefType "journal-article" @default.
• W1981985293 hasAuthorship W1981985293A5005906334 @default.
• W1981985293 hasAuthorship W1981985293A5014695714 @default.
• W1981985293 hasAuthorship W1981985293A5020796809 @default.
• W1981985293 hasAuthorship W1981985293A5032091947 @default.
• W1981985293 hasConcept C118552586 @default.
• W1981985293 hasConcept C126322002 @default.
• W1981985293 hasConcept C139719470 @default.
• W1981985293 hasConcept C15744967 @default.
• W1981985293 hasConcept C162324750 @default.
• W1981985293 hasConcept C2776174506 @default.
• W1981985293 hasConcept C2776809841 @default.
• W1981985293 hasConcept C2776867660 @default.
• W1981985293 hasConcept C2778186239 @default.
• W1981985293 hasConcept C2778715236 @default.
• W1981985293 hasConcept C2778802184 @default.
• W1981985293 hasConcept C2780550438 @default.
• W1981985293 hasConcept C2780733359 @default.
• W1981985293 hasConcept C3018162438 @default.
• W1981985293 hasConcept C71924100 @default.
• W1981985293 hasConceptScore W1981985293C118552586 @default.
• W1981985293 hasConceptScore W1981985293C126322002 @default.
• W1981985293 hasConceptScore W1981985293C139719470 @default.
• W1981985293 hasConceptScore W1981985293C15744967 @default.
• W1981985293 hasConceptScore W1981985293C162324750 @default.
• W1981985293 hasConceptScore W1981985293C2776174506 @default.
• W1981985293 hasConceptScore W1981985293C2776809841 @default.
• W1981985293 hasConceptScore W1981985293C2776867660 @default.
• W1981985293 hasConceptScore W1981985293C2778186239 @default.
• W1981985293 hasConceptScore W1981985293C2778715236 @default.
• W1981985293 hasConceptScore W1981985293C2778802184 @default.
• W1981985293 hasConceptScore W1981985293C2780550438 @default.
• W1981985293 hasConceptScore W1981985293C2780733359 @default.
• W1981985293 hasConceptScore W1981985293C3018162438 @default.
• W1981985293 hasConceptScore W1981985293C71924100 @default.
• W1981985293 hasIssue "7" @default.
• W1981985293 hasLocation W19819852931 @default.
• W1981985293 hasLocation W19819852932 @default.
• W1981985293 hasOpenAccess W1981985293 @default.
• W1981985293 hasPrimaryLocation W19819852931 @default.
• W1981985293 hasRelatedWork W1935710421 @default.
• W1981985293 hasRelatedWork W2004959256 @default.

• next