Matches in SemOpenAlex for { <https://semopenalex.org/work/W1981990979> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W1981990979 endingPage "345" @default.
- W1981990979 startingPage "338" @default.
- W1981990979 abstract "The structural and functional similarities between Müller cells and oligodendrocytes prompted the present study of the electrophysiological properties of Müller (glia) cells obtained from the retinae of control and myelin mutant taiep rats during the postnatal developmental period (P12–P180). The whole-cell configuration of the patch-clamp technique was used to characterize the general properties and the K+ currents from dissociated Müller cells. During the first 3 weeks of life, a decrease of the membrane resistance and an increase of the membrane potential were observed in Müller cells from both control and taiep rats. However, Müller cells from taiep rats never achieved the very negative membrane potential (−50 mV vs −80 mV) and the low membrane resistance characteristic for control cells. Furthermore, Müller cells displayed increased inward and outward K+ currents during postnatal development up to P30/60 in controls; however, in taiep rats, this increase ceased at P20/30, and low-amplitude currents persisted into adulthood. These results provide first evidence of physiological changes in retinal Müller cells as a consequence of a myelin mutation causing a progressive deterioration of the central nervous system (CNS) due to a disturbance of the microtubule network of oligodendrocytes. We hypothesize that the progressive dysmyelination process of the optic nerve, accompanied by functional deficits of retinal neurons (e.g., ganglion cells), induces physiological alterations of Müller cells. © 2003 Wiley-Liss, Inc." @default.
- W1981990979 created "2016-06-24" @default.
- W1981990979 creator A5002410378 @default.
- W1981990979 creator A5045138697 @default.
- W1981990979 creator A5061791905 @default.
- W1981990979 creator A5068456297 @default.
- W1981990979 creator A5082241507 @default.
- W1981990979 date "2003-12-12" @default.
- W1981990979 modified "2023-10-09" @default.
- W1981990979 title "Electrophysiological properties of retinal Müller glial cells from myelin mutant rat" @default.
- W1981990979 cites W1967754815 @default.
- W1981990979 cites W1973672173 @default.
- W1981990979 cites W1978461630 @default.
- W1981990979 cites W1984559839 @default.
- W1981990979 cites W1984794327 @default.
- W1981990979 cites W1994626566 @default.
- W1981990979 cites W1995911845 @default.
- W1981990979 cites W1998580170 @default.
- W1981990979 cites W2001012585 @default.
- W1981990979 cites W2001545716 @default.
- W1981990979 cites W2011863717 @default.
- W1981990979 cites W2016723523 @default.
- W1981990979 cites W2027233210 @default.
- W1981990979 cites W2028245723 @default.
- W1981990979 cites W2031384113 @default.
- W1981990979 cites W2033412905 @default.
- W1981990979 cites W2035936196 @default.
- W1981990979 cites W2046229926 @default.
- W1981990979 cites W2051953163 @default.
- W1981990979 cites W2071915726 @default.
- W1981990979 cites W2146262948 @default.
- W1981990979 cites W2163161737 @default.
- W1981990979 cites W28039053 @default.
- W1981990979 doi "https://doi.org/10.1002/glia.10330" @default.
- W1981990979 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14966865" @default.
- W1981990979 hasPublicationYear "2003" @default.
- W1981990979 type Work @default.
- W1981990979 sameAs 1981990979 @default.
- W1981990979 citedByCount "2" @default.
- W1981990979 countsByYear W19819909792015 @default.
- W1981990979 crossrefType "journal-article" @default.
- W1981990979 hasAuthorship W1981990979A5002410378 @default.
- W1981990979 hasAuthorship W1981990979A5045138697 @default.
- W1981990979 hasAuthorship W1981990979A5061791905 @default.
- W1981990979 hasAuthorship W1981990979A5068456297 @default.
- W1981990979 hasAuthorship W1981990979A5082241507 @default.
- W1981990979 hasConcept C147944092 @default.
- W1981990979 hasConcept C169760540 @default.
- W1981990979 hasConcept C181911157 @default.
- W1981990979 hasConcept C185263204 @default.
- W1981990979 hasConcept C2776985911 @default.
- W1981990979 hasConcept C2777093970 @default.
- W1981990979 hasConcept C2778609137 @default.
- W1981990979 hasConcept C2780827179 @default.
- W1981990979 hasConcept C2780837183 @default.
- W1981990979 hasConcept C2780884517 @default.
- W1981990979 hasConcept C529278444 @default.
- W1981990979 hasConcept C55493867 @default.
- W1981990979 hasConcept C86803240 @default.
- W1981990979 hasConcept C95444343 @default.
- W1981990979 hasConceptScore W1981990979C147944092 @default.
- W1981990979 hasConceptScore W1981990979C169760540 @default.
- W1981990979 hasConceptScore W1981990979C181911157 @default.
- W1981990979 hasConceptScore W1981990979C185263204 @default.
- W1981990979 hasConceptScore W1981990979C2776985911 @default.
- W1981990979 hasConceptScore W1981990979C2777093970 @default.
- W1981990979 hasConceptScore W1981990979C2778609137 @default.
- W1981990979 hasConceptScore W1981990979C2780827179 @default.
- W1981990979 hasConceptScore W1981990979C2780837183 @default.
- W1981990979 hasConceptScore W1981990979C2780884517 @default.
- W1981990979 hasConceptScore W1981990979C529278444 @default.
- W1981990979 hasConceptScore W1981990979C55493867 @default.
- W1981990979 hasConceptScore W1981990979C86803240 @default.
- W1981990979 hasConceptScore W1981990979C95444343 @default.
- W1981990979 hasIssue "4" @default.
- W1981990979 hasLocation W19819909791 @default.
- W1981990979 hasLocation W19819909792 @default.
- W1981990979 hasOpenAccess W1981990979 @default.
- W1981990979 hasPrimaryLocation W19819909791 @default.
- W1981990979 hasRelatedWork W1534176032 @default.
- W1981990979 hasRelatedWork W1975603025 @default.
- W1981990979 hasRelatedWork W1978398040 @default.
- W1981990979 hasRelatedWork W1985495387 @default.
- W1981990979 hasRelatedWork W1990726019 @default.
- W1981990979 hasRelatedWork W2003803320 @default.
- W1981990979 hasRelatedWork W2028975896 @default.
- W1981990979 hasRelatedWork W2061193012 @default.
- W1981990979 hasRelatedWork W2072990016 @default.
- W1981990979 hasRelatedWork W95250996 @default.
- W1981990979 hasVolume "45" @default.
- W1981990979 isParatext "false" @default.
- W1981990979 isRetracted "false" @default.
- W1981990979 magId "1981990979" @default.
- W1981990979 workType "article" @default.