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• W1982005911 abstract "One of the most intriguing gaps in our understanding of how neutrophils work concerns the mechanism by which the oxidase response in these cells is ‘primed’. In the primed state, there is no increase in oxidase activity, yet subsequent stimulation provokes a response that is larger than in non-primed, activated cells. Thus, neutrophils exist in one of three states: quiescent, primed or active. Individual primed cells may be thought of as being ‘ready to go’ but awaiting further stimulus before the oxidase response is elicited. The primed neutrophils are thus held at ‘amber’, awaiting ‘green’ before activity is triggered. Here, Maurice Hallett and Darren Lloyds suggest a molecular basis for the signals that say ‘amber’ but not ‘green’." @default.
• W1982005911 created "2016-06-24" @default.
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• W1982005911 date "1995-06-01" @default.
• W1982005911 modified "2023-09-30" @default.
• W1982005911 title "Neutrophil priming: the cellular signals that say ‘amber’ but not ‘green’" @default.
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• W1982005911 doi "https://doi.org/10.1016/0167-5699(95)80178-2" @default.
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