Matches in SemOpenAlex for { <https://semopenalex.org/work/W1982027200> ?p ?o ?g. }
- W1982027200 abstract "Gastro-oesophageal reflux disease (GORD) symptoms are common in asthma and have been extensively studied, but less so in the Asian continent. Reflux-associated respiratory symptoms (RARS) have, in contrast, been little-studied globally. We report the prevalence of GORD symptoms and RARS in adult asthmatics, and their association with asthma severity and medication use.A cross-sectional analytical study. A validated interviewer-administered GORD scale was used to assess frequency and severity of seven GORD symptoms. Subjects were consecutive asthmatics attending medical clinics. Controls were matched subjects without respiratory symptoms.The mean (SD) composite GORD symptom score of asthmatics was significantly higher than controls (21.8 (17.2) versus 12.0 (7.6); P < 0.001) as was frequency of each symptom and RARS. Prevalence of GORD symptoms in asthmatics was 59.4% (95% CI, 59.1%-59.6%) versus 28.5% in controls (95% CI, 29.0% - 29.4%). 36% of asthmatics experienced respiratory symptoms in association with both typical and atypical GORD symptoms, compared to 10% of controls (P < 0.001). An asthmatic had a 3.5 times higher risk of experiencing a GORD symptom after adjusting for confounders (OR 3.5; 95% CI 2.5-5.3). Severity of asthma had a strong dose-response relationship with GORD symptoms. Asthma medication use did not significantly influence the presence of GORD symptoms.GORD symptoms and RARS were more prevalent in a cohort of Sri Lankan adult asthmatics compared to non-asthmatics. Increased prevalence of RARS is associated with both typical and atypical symptoms of GORD. Asthma disease and its severity, but not asthma medication, appear to influence presence of GORD symptoms." @default.
- W1982027200 created "2016-06-24" @default.
- W1982027200 creator A5009730247 @default.
- W1982027200 creator A5028712127 @default.
- W1982027200 creator A5063814256 @default.
- W1982027200 creator A5069898979 @default.
- W1982027200 date "2010-09-15" @default.
- W1982027200 modified "2023-10-18" @default.
- W1982027200 title "Prevalence of gastro-oesophageal reflux disease symptoms and reflux-associated respiratory symptoms in asthma" @default.
- W1982027200 cites W1647392156 @default.
- W1982027200 cites W186042427 @default.
- W1982027200 cites W1965863574 @default.
- W1982027200 cites W1971442238 @default.
- W1982027200 cites W1976459990 @default.
- W1982027200 cites W1983948911 @default.
- W1982027200 cites W1995808193 @default.
- W1982027200 cites W2002350900 @default.
- W1982027200 cites W2002945047 @default.
- W1982027200 cites W2007503510 @default.
- W1982027200 cites W2010150233 @default.
- W1982027200 cites W2016540015 @default.
- W1982027200 cites W2017578760 @default.
- W1982027200 cites W2021378871 @default.
- W1982027200 cites W2029152648 @default.
- W1982027200 cites W2032933359 @default.
- W1982027200 cites W2034804696 @default.
- W1982027200 cites W2041274891 @default.
- W1982027200 cites W2046461540 @default.
- W1982027200 cites W2048923534 @default.
- W1982027200 cites W2057239514 @default.
- W1982027200 cites W2060974098 @default.
- W1982027200 cites W2067455414 @default.
- W1982027200 cites W2071313378 @default.
- W1982027200 cites W2084306438 @default.
- W1982027200 cites W2096758679 @default.
- W1982027200 cites W2107657525 @default.
- W1982027200 cites W2112973823 @default.
- W1982027200 cites W2118892918 @default.
- W1982027200 cites W2128779022 @default.
- W1982027200 cites W2131795449 @default.
- W1982027200 cites W2153516163 @default.
- W1982027200 doi "https://doi.org/10.1186/1471-2466-10-49" @default.
- W1982027200 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2954896" @default.
- W1982027200 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20843346" @default.
- W1982027200 hasPublicationYear "2010" @default.
- W1982027200 type Work @default.
- W1982027200 sameAs 1982027200 @default.
- W1982027200 citedByCount "18" @default.
- W1982027200 countsByYear W19820272002013 @default.
- W1982027200 countsByYear W19820272002014 @default.
- W1982027200 countsByYear W19820272002015 @default.
- W1982027200 countsByYear W19820272002016 @default.
- W1982027200 countsByYear W19820272002017 @default.
- W1982027200 countsByYear W19820272002018 @default.
- W1982027200 countsByYear W19820272002020 @default.
- W1982027200 countsByYear W19820272002021 @default.
- W1982027200 countsByYear W19820272002022 @default.
- W1982027200 countsByYear W19820272002023 @default.
- W1982027200 crossrefType "journal-article" @default.
- W1982027200 hasAuthorship W1982027200A5009730247 @default.
- W1982027200 hasAuthorship W1982027200A5028712127 @default.
- W1982027200 hasAuthorship W1982027200A5063814256 @default.
- W1982027200 hasAuthorship W1982027200A5069898979 @default.
- W1982027200 hasBestOaLocation W19820272001 @default.
- W1982027200 hasConcept C126322002 @default.
- W1982027200 hasConcept C201903717 @default.
- W1982027200 hasConcept C22130703 @default.
- W1982027200 hasConcept C2776042228 @default.
- W1982027200 hasConcept C2776178081 @default.
- W1982027200 hasConcept C2777014526 @default.
- W1982027200 hasConcept C2777714996 @default.
- W1982027200 hasConcept C2779134260 @default.
- W1982027200 hasConcept C43270747 @default.
- W1982027200 hasConcept C534529494 @default.
- W1982027200 hasConcept C71924100 @default.
- W1982027200 hasConcept C72563966 @default.
- W1982027200 hasConcept C77350462 @default.
- W1982027200 hasConcept C90924648 @default.
- W1982027200 hasConceptScore W1982027200C126322002 @default.
- W1982027200 hasConceptScore W1982027200C201903717 @default.
- W1982027200 hasConceptScore W1982027200C22130703 @default.
- W1982027200 hasConceptScore W1982027200C2776042228 @default.
- W1982027200 hasConceptScore W1982027200C2776178081 @default.
- W1982027200 hasConceptScore W1982027200C2777014526 @default.
- W1982027200 hasConceptScore W1982027200C2777714996 @default.
- W1982027200 hasConceptScore W1982027200C2779134260 @default.
- W1982027200 hasConceptScore W1982027200C43270747 @default.
- W1982027200 hasConceptScore W1982027200C534529494 @default.
- W1982027200 hasConceptScore W1982027200C71924100 @default.
- W1982027200 hasConceptScore W1982027200C72563966 @default.
- W1982027200 hasConceptScore W1982027200C77350462 @default.
- W1982027200 hasConceptScore W1982027200C90924648 @default.
- W1982027200 hasIssue "1" @default.
- W1982027200 hasLocation W19820272001 @default.
- W1982027200 hasLocation W19820272002 @default.
- W1982027200 hasLocation W19820272003 @default.
- W1982027200 hasLocation W19820272004 @default.
- W1982027200 hasOpenAccess W1982027200 @default.
- W1982027200 hasPrimaryLocation W19820272001 @default.
- W1982027200 hasRelatedWork W2041297026 @default.