Matches in SemOpenAlex for { <https://semopenalex.org/work/W1982031291> ?p ?o ?g. }
- W1982031291 endingPage "2133" @default.
- W1982031291 startingPage "2127" @default.
- W1982031291 abstract "BACKGROUND. Malignant phyllodes tumor is a rare and potentially aggressive breast neoplasm. Little information is available regarding the optimal management of these lesions and rarer still are data regarding survival. The current study used a large population database to determine prognostic factors that predict cause-specific survival (CSS). METHODS. Data were obtained from the Surveillance, Epidemiology, and End Results Program (SEER) for the years 1983–2002. Women receiving resection for primary nonmetastatic malignant phyllodes tumor of the breast were included (n = 821). Analyses of patient, pathologic, and treatment characteristics were performed using univariate and multivariate Cox regression analyses for the CSS endpoint. RESULTS. With a median follow-up of 5.7 years, CSS was 91%, 89%, and 89%, at 5, 10, and 15 years, respectively. Mastectomy was performed in 428 women (52%) and wide excision or lumpectomy in 393 (48%). Women undergoing mastectomy were significantly older (P = .004) and had larger tumors (P = .009). Wide excision was associated with equivalent or improved CSS relative to mastectomy on univariate and multivariate analyses. Older age predicted for cause-specific mortality on multivariate analysis. Adjuvant radiotherapy (RT) predicted for worse CSS when implemented compared with surgery alone. CONCLUSIONS. Mastectomy was not found to provide a benefit in CSS compared with wide excision in malignant phyllodes tumor of the breast. Women undergoing wide excision had at the minimum similar cancer-specific mortality compared with those who received mastectomy. The role of adjuvant RT is uncertain and requires further investigation. Cancer 2006. © 2006 American Cancer Society." @default.
- W1982031291 created "2016-06-24" @default.
- W1982031291 creator A5037810145 @default.
- W1982031291 creator A5040908498 @default.
- W1982031291 creator A5048614370 @default.
- W1982031291 creator A5057224046 @default.
- W1982031291 creator A5065037241 @default.
- W1982031291 date "2006-01-01" @default.
- W1982031291 modified "2023-10-05" @default.
- W1982031291 title "Malignant phyllodes tumor of the female breast" @default.
- W1982031291 cites W1976574140 @default.
- W1982031291 cites W1988037893 @default.
- W1982031291 cites W1992915425 @default.
- W1982031291 cites W2018677166 @default.
- W1982031291 cites W2025426750 @default.
- W1982031291 cites W2045326078 @default.
- W1982031291 cites W2046456514 @default.
- W1982031291 cites W2063658064 @default.
- W1982031291 cites W2064956179 @default.
- W1982031291 cites W2069904849 @default.
- W1982031291 cites W2093395615 @default.
- W1982031291 cites W2093497641 @default.
- W1982031291 cites W2100895397 @default.
- W1982031291 cites W2103240146 @default.
- W1982031291 cites W2410762156 @default.
- W1982031291 cites W2473555490 @default.
- W1982031291 cites W2526102152 @default.
- W1982031291 cites W2801690730 @default.
- W1982031291 cites W4237244869 @default.
- W1982031291 cites W4251028919 @default.
- W1982031291 cites W4293241248 @default.
- W1982031291 doi "https://doi.org/10.1002/cncr.22228" @default.
- W1982031291 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16998937" @default.
- W1982031291 hasPublicationYear "2006" @default.
- W1982031291 type Work @default.
- W1982031291 sameAs 1982031291 @default.
- W1982031291 citedByCount "187" @default.
- W1982031291 countsByYear W19820312912012 @default.
- W1982031291 countsByYear W19820312912013 @default.
- W1982031291 countsByYear W19820312912014 @default.
- W1982031291 countsByYear W19820312912015 @default.
- W1982031291 countsByYear W19820312912016 @default.
- W1982031291 countsByYear W19820312912017 @default.
- W1982031291 countsByYear W19820312912018 @default.
- W1982031291 countsByYear W19820312912019 @default.
- W1982031291 countsByYear W19820312912020 @default.
- W1982031291 countsByYear W19820312912021 @default.
- W1982031291 countsByYear W19820312912022 @default.
- W1982031291 countsByYear W19820312912023 @default.
- W1982031291 crossrefType "journal-article" @default.
- W1982031291 hasAuthorship W1982031291A5037810145 @default.
- W1982031291 hasAuthorship W1982031291A5040908498 @default.
- W1982031291 hasAuthorship W1982031291A5048614370 @default.
- W1982031291 hasAuthorship W1982031291A5057224046 @default.
- W1982031291 hasAuthorship W1982031291A5065037241 @default.
- W1982031291 hasBestOaLocation W19820312911 @default.
- W1982031291 hasConcept C121608353 @default.
- W1982031291 hasConcept C126322002 @default.
- W1982031291 hasConcept C141071460 @default.
- W1982031291 hasConcept C143998085 @default.
- W1982031291 hasConcept C144301174 @default.
- W1982031291 hasConcept C2777757722 @default.
- W1982031291 hasConcept C2779572924 @default.
- W1982031291 hasConcept C2908647359 @default.
- W1982031291 hasConcept C29456083 @default.
- W1982031291 hasConcept C38180746 @default.
- W1982031291 hasConcept C50382708 @default.
- W1982031291 hasConcept C509974204 @default.
- W1982031291 hasConcept C530470458 @default.
- W1982031291 hasConcept C71924100 @default.
- W1982031291 hasConcept C99454951 @default.
- W1982031291 hasConceptScore W1982031291C121608353 @default.
- W1982031291 hasConceptScore W1982031291C126322002 @default.
- W1982031291 hasConceptScore W1982031291C141071460 @default.
- W1982031291 hasConceptScore W1982031291C143998085 @default.
- W1982031291 hasConceptScore W1982031291C144301174 @default.
- W1982031291 hasConceptScore W1982031291C2777757722 @default.
- W1982031291 hasConceptScore W1982031291C2779572924 @default.
- W1982031291 hasConceptScore W1982031291C2908647359 @default.
- W1982031291 hasConceptScore W1982031291C29456083 @default.
- W1982031291 hasConceptScore W1982031291C38180746 @default.
- W1982031291 hasConceptScore W1982031291C50382708 @default.
- W1982031291 hasConceptScore W1982031291C509974204 @default.
- W1982031291 hasConceptScore W1982031291C530470458 @default.
- W1982031291 hasConceptScore W1982031291C71924100 @default.
- W1982031291 hasConceptScore W1982031291C99454951 @default.
- W1982031291 hasIssue "9" @default.
- W1982031291 hasLocation W19820312911 @default.
- W1982031291 hasLocation W19820312912 @default.
- W1982031291 hasOpenAccess W1982031291 @default.
- W1982031291 hasPrimaryLocation W19820312911 @default.
- W1982031291 hasRelatedWork W1990137448 @default.
- W1982031291 hasRelatedWork W2058002784 @default.
- W1982031291 hasRelatedWork W2059347310 @default.
- W1982031291 hasRelatedWork W2361700749 @default.
- W1982031291 hasRelatedWork W2375813207 @default.
- W1982031291 hasRelatedWork W2389549616 @default.
- W1982031291 hasRelatedWork W2417530735 @default.