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- W1982037837 abstract "We investigated the expression and cellular localization of neuronal nitric oxide synthase (nNOS) in the rat retina, following ischemic injury induced by transient increase of intraocular pressure. In the normal retina, nNOS immunoreactivity was localized to certain populations of amacrine cells, displaced amacrine cells and a few bipolar cells. Following transient ischemia, retinal neurons expressing the immunoreactivity increased and peaked three days after reperfusion. Quantitative evaluation using immunoblotting confirmed that nNOS expression showed a peak value (500% of control levels) at 3 days, and then decreased again to 150% of controls by 4 weeks after reperfusion. Our findings suggest that this over-produced NO may act as a neurotoxic agent in the ischemic rat retina." @default.
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- W1982037837 date "2001-10-01" @default.
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- W1982037837 title "The regulatory expression of neuronal nitric oxide synthase in the ischemic rat retina" @default.
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- W1982037837 doi "https://doi.org/10.1097/00001756-200110290-00047" @default.
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