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• W1982074551 abstract "We have isolated and characterized proglucagon cDNAs from the intestine and pancreas of the leopard frog Rana pipiens. R. pipiens proglucagon encodes glucagon, glucagon-like peptides 2 (GLP-2), and two glucagon-like peptide 1 (GLP-1) like sequences. The pancreatic and intestinal cDNAs were of identical structure and sequence suggesting that, unlike many other non-mammalian vertebrates, there is little or no alternative splicing of the proglucagon mRNA in this species. A phylogenetic analysis of the GLP-1 encoding sequences implies that the exon encoding GLP-1 was triplicated early in frog evolution, more than 150 million years ago, before the divergence of modern frogs." @default.
• W1982074551 created "2016-06-24" @default.
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• W1982074551 date "2000-04-01" @default.
• W1982074551 modified "2023-09-23" @default.
• W1982074551 title "Proglucagon cDNAs from the Leopard Frog, Rana pipiens, encode two GLP-1-like peptides" @default.
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• W1982074551 doi "https://doi.org/10.1016/s0303-7207(00)00229-x" @default.
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