Matches in SemOpenAlex for { <https://semopenalex.org/work/W1982079498> ?p ?o ?g. }
- W1982079498 endingPage "860" @default.
- W1982079498 startingPage "849" @default.
- W1982079498 abstract "Adenosine deaminases acting on RNA (ADARs) convert adenosine to inosine, which is then recognized as guanosine. To study the role of ADAR proteins in RNA editing and gene regulation, we sequenced and compared the DNA and RNA of human B cells. Then, we followed up the findings experimentally with siRNA knockdown and RNA and protein immunoprecipitations. The results uncovered over 60,000 A-to-G editing sites and several thousand genes whose expression levels are influenced by ADARs. Of these ADAR targets, 90% were identified. Our results also reveal that ADAR regulates transcript stability and gene expression through interaction with HuR (ELAVL1). These findings extend the role of ADAR and show that it cooperates with other RNA-processing proteins to regulate the sequence and expression of transcripts in human cells." @default.
- W1982079498 created "2016-06-24" @default.
- W1982079498 creator A5032003836 @default.
- W1982079498 creator A5046336449 @default.
- W1982079498 creator A5046476461 @default.
- W1982079498 creator A5055573790 @default.
- W1982079498 creator A5058198170 @default.
- W1982079498 creator A5064550476 @default.
- W1982079498 date "2013-11-01" @default.
- W1982079498 modified "2023-10-17" @default.
- W1982079498 title "ADAR Regulates RNA Editing, Transcript Stability, and Gene Expression" @default.
- W1982079498 cites W1966933803 @default.
- W1982079498 cites W1968302884 @default.
- W1982079498 cites W1970577477 @default.
- W1982079498 cites W1977957409 @default.
- W1982079498 cites W1989656471 @default.
- W1982079498 cites W1990478192 @default.
- W1982079498 cites W1996063915 @default.
- W1982079498 cites W2001795351 @default.
- W1982079498 cites W2003451384 @default.
- W1982079498 cites W2006931677 @default.
- W1982079498 cites W2012016911 @default.
- W1982079498 cites W2017472306 @default.
- W1982079498 cites W2022590976 @default.
- W1982079498 cites W2026284791 @default.
- W1982079498 cites W2033385373 @default.
- W1982079498 cites W2042436354 @default.
- W1982079498 cites W2044136480 @default.
- W1982079498 cites W2049972042 @default.
- W1982079498 cites W2050002679 @default.
- W1982079498 cites W2050108172 @default.
- W1982079498 cites W2059073003 @default.
- W1982079498 cites W2059646461 @default.
- W1982079498 cites W2062714021 @default.
- W1982079498 cites W2069084578 @default.
- W1982079498 cites W2076961967 @default.
- W1982079498 cites W2079859830 @default.
- W1982079498 cites W2082102894 @default.
- W1982079498 cites W2083443360 @default.
- W1982079498 cites W2090009109 @default.
- W1982079498 cites W2091712692 @default.
- W1982079498 cites W2096259566 @default.
- W1982079498 cites W2100000928 @default.
- W1982079498 cites W2103017472 @default.
- W1982079498 cites W2109282318 @default.
- W1982079498 cites W2118560713 @default.
- W1982079498 cites W2122141117 @default.
- W1982079498 cites W2123497973 @default.
- W1982079498 cites W2129424750 @default.
- W1982079498 cites W2133465414 @default.
- W1982079498 cites W2137786443 @default.
- W1982079498 cites W2147596164 @default.
- W1982079498 cites W2149217126 @default.
- W1982079498 cites W2149480306 @default.
- W1982079498 cites W2157009395 @default.
- W1982079498 cites W2157815953 @default.
- W1982079498 cites W2158166257 @default.
- W1982079498 cites W2158217645 @default.
- W1982079498 cites W2159376549 @default.
- W1982079498 cites W2161048703 @default.
- W1982079498 cites W2161556727 @default.
- W1982079498 cites W2166820820 @default.
- W1982079498 cites W2168046699 @default.
- W1982079498 cites W3102334290 @default.
- W1982079498 doi "https://doi.org/10.1016/j.celrep.2013.10.002" @default.
- W1982079498 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3935819" @default.
- W1982079498 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24183664" @default.
- W1982079498 hasPublicationYear "2013" @default.
- W1982079498 type Work @default.
- W1982079498 sameAs 1982079498 @default.
- W1982079498 citedByCount "159" @default.
- W1982079498 countsByYear W19820794982013 @default.
- W1982079498 countsByYear W19820794982014 @default.
- W1982079498 countsByYear W19820794982015 @default.
- W1982079498 countsByYear W19820794982016 @default.
- W1982079498 countsByYear W19820794982017 @default.
- W1982079498 countsByYear W19820794982018 @default.
- W1982079498 countsByYear W19820794982019 @default.
- W1982079498 countsByYear W19820794982020 @default.
- W1982079498 countsByYear W19820794982021 @default.
- W1982079498 countsByYear W19820794982022 @default.
- W1982079498 countsByYear W19820794982023 @default.
- W1982079498 crossrefType "journal-article" @default.
- W1982079498 hasAuthorship W1982079498A5032003836 @default.
- W1982079498 hasAuthorship W1982079498A5046336449 @default.
- W1982079498 hasAuthorship W1982079498A5046476461 @default.
- W1982079498 hasAuthorship W1982079498A5055573790 @default.
- W1982079498 hasAuthorship W1982079498A5058198170 @default.
- W1982079498 hasAuthorship W1982079498A5064550476 @default.
- W1982079498 hasBestOaLocation W19820794981 @default.
- W1982079498 hasConcept C104317684 @default.
- W1982079498 hasConcept C105580179 @default.
- W1982079498 hasConcept C150194340 @default.
- W1982079498 hasConcept C153911025 @default.
- W1982079498 hasConcept C165864922 @default.
- W1982079498 hasConcept C166703698 @default.
- W1982079498 hasConcept C173396325 @default.
- W1982079498 hasConcept C21786251 @default.