Matches in SemOpenAlex for { <https://semopenalex.org/work/W1982113013> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W1982113013 abstract "We determined whether regional myocardial work efficiency (segment work/regional O2 consumption) would be elevated by surgically-augmented inflow. In 10 anesthetized open-chest dogs, shunt between the ascending aorta and the superior vena cava was used to increase cardiac output. Hetastarch (15 ml/kg) was infused before opening the shunt to maintain coronary perfusion pressure. Regional myocardial segment work and O2 consumption (MVO2) were measured, during control and two levels of elevated flow. Regional segment work (g.mm/min) was calculated as the integrated products of force (g - miniature transducer) and segment shortening (mm - ultrasonic dimension gauge) during an averaged beat expressed per minute. Local MVO2 (ml O2/min/100g) was calculated from regional blood flow (microspheres) and O2 saturations (microspectrophotometry). It was found that regional myocardial segment work increased significantly (P < 0.05) from 926 +/- 94 to 1656 +/- 220 to 1479 +/- 309 (g.mm/min) for closed, half-open, and open shunt. This increase was primarily associated with increased segment shortening (from 147 +/- 14.1 to 204.4 +/- 20.1 to 232 +/- 26.1 mm/min). Both force development and regional MVO2 were unchanged during the experiment. Regional myocardial efficiency was significantly elevated during shunt function (from 95 +/- 12 to 187 +/- 31 to 213 +/- 57 g.mm/ml O2/100g). Systolic ejection stiffness (defined as the slope of the force-length relationship during the period of ejection) decreased from 8.0 +/- 0.9 to 4.7 +/- 0.4 to 4.5 +/- 0.9 g/mm during elevated inflow. It is concluded that when cardiac work is augmented primarily by segment shortening, regional myocardial efficiency is improved. This improvement is associated with decreased resistance to shortening (stiffness)." @default.
- W1982113013 created "2016-06-24" @default.
- W1982113013 creator A5007661483 @default.
- W1982113013 creator A5038761711 @default.
- W1982113013 creator A5073349248 @default.
- W1982113013 creator A5078027078 @default.
- W1982113013 date "1994-01-01" @default.
- W1982113013 modified "2023-09-23" @default.
- W1982113013 title "Regional myocardial efficiency is improved in experimental aorto-caval shunt" @default.
- W1982113013 cites W1514274214 @default.
- W1982113013 cites W1968229578 @default.
- W1982113013 cites W1978278112 @default.
- W1982113013 cites W1991064387 @default.
- W1982113013 cites W2007596664 @default.
- W1982113013 cites W2071939396 @default.
- W1982113013 cites W2073754852 @default.
- W1982113013 cites W2095656943 @default.
- W1982113013 cites W2096084168 @default.
- W1982113013 cites W2114122936 @default.
- W1982113013 cites W2154777680 @default.
- W1982113013 cites W2158362201 @default.
- W1982113013 cites W2336032867 @default.
- W1982113013 cites W2398211025 @default.
- W1982113013 cites W2410317274 @default.
- W1982113013 cites W2412884084 @default.
- W1982113013 cites W2418515835 @default.
- W1982113013 doi "https://doi.org/10.3109/13813459408996123" @default.
- W1982113013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7519463" @default.
- W1982113013 hasPublicationYear "1994" @default.
- W1982113013 type Work @default.
- W1982113013 sameAs 1982113013 @default.
- W1982113013 citedByCount "3" @default.
- W1982113013 crossrefType "journal-article" @default.
- W1982113013 hasAuthorship W1982113013A5007661483 @default.
- W1982113013 hasAuthorship W1982113013A5038761711 @default.
- W1982113013 hasAuthorship W1982113013A5073349248 @default.
- W1982113013 hasAuthorship W1982113013A5078027078 @default.
- W1982113013 hasConcept C111566952 @default.
- W1982113013 hasConcept C126322002 @default.
- W1982113013 hasConcept C139940330 @default.
- W1982113013 hasConcept C146957229 @default.
- W1982113013 hasConcept C164705383 @default.
- W1982113013 hasConcept C178853913 @default.
- W1982113013 hasConcept C185592680 @default.
- W1982113013 hasConcept C2778198053 @default.
- W1982113013 hasConcept C2778249958 @default.
- W1982113013 hasConcept C2779980429 @default.
- W1982113013 hasConcept C2780968331 @default.
- W1982113013 hasConcept C42219234 @default.
- W1982113013 hasConcept C71924100 @default.
- W1982113013 hasConcept C99398487 @default.
- W1982113013 hasConceptScore W1982113013C111566952 @default.
- W1982113013 hasConceptScore W1982113013C126322002 @default.
- W1982113013 hasConceptScore W1982113013C139940330 @default.
- W1982113013 hasConceptScore W1982113013C146957229 @default.
- W1982113013 hasConceptScore W1982113013C164705383 @default.
- W1982113013 hasConceptScore W1982113013C178853913 @default.
- W1982113013 hasConceptScore W1982113013C185592680 @default.
- W1982113013 hasConceptScore W1982113013C2778198053 @default.
- W1982113013 hasConceptScore W1982113013C2778249958 @default.
- W1982113013 hasConceptScore W1982113013C2779980429 @default.
- W1982113013 hasConceptScore W1982113013C2780968331 @default.
- W1982113013 hasConceptScore W1982113013C42219234 @default.
- W1982113013 hasConceptScore W1982113013C71924100 @default.
- W1982113013 hasConceptScore W1982113013C99398487 @default.
- W1982113013 hasLocation W19821130131 @default.
- W1982113013 hasLocation W19821130132 @default.
- W1982113013 hasOpenAccess W1982113013 @default.
- W1982113013 hasPrimaryLocation W19821130131 @default.
- W1982113013 hasRelatedWork W1965448675 @default.
- W1982113013 hasRelatedWork W1969922016 @default.
- W1982113013 hasRelatedWork W1980490379 @default.
- W1982113013 hasRelatedWork W2009113312 @default.
- W1982113013 hasRelatedWork W2026225557 @default.
- W1982113013 hasRelatedWork W2110714461 @default.
- W1982113013 hasRelatedWork W2111300986 @default.
- W1982113013 hasRelatedWork W2403697258 @default.
- W1982113013 hasRelatedWork W4226369833 @default.
- W1982113013 hasRelatedWork W4245203202 @default.
- W1982113013 isParatext "false" @default.
- W1982113013 isRetracted "false" @default.
- W1982113013 magId "1982113013" @default.
- W1982113013 workType "article" @default.