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- W1982113823 abstract "N-nitroso-2-hydroxymorpholine, a mutagenic metabolite of N-nitrosomorpholine and N-nitrosodiethanolamine, reacted with deoxyguanosine at pH 7, 37°C, to give 3-(2-deoxy-β-D-erythropentofuranosyI)-6, 7-dihydro-6, 7-dihydroxyimidazo-[1, 2-a]purine-9(3H)one, which is also formed by reaction of deoxyguanosine with glyoxal. The results suggest that this adduct might be involved in DNA binding by N-nitrosomorpholine and N-nitrosodiethanolamine." @default.
- W1982113823 created "2016-06-24" @default.
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- W1982113823 date "1985-01-01" @default.
- W1982113823 modified "2023-10-17" @default.
- W1982113823 title "Formation of the cyclic 1,N<sup>2</sup>-glyoxal-deoxyguanosine adduct upon reaction of N-nitroso-2-hydroxymorpholine with deoxyguanosine" @default.
- W1982113823 doi "https://doi.org/10.1093/carcin/6.11.1671" @default.
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