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- W1982118557 abstract "In this work, electrospray ionization mass spectrometry (ESI MS) was employed to study the interactions of cobalt(III) hexammine, Co(NH3)63+, with five RNA hairpins representing the 790 loop of 16S ribosomal RNA and 1920 loop of 23S ribosomal RNA. The RNAs varied in mismatch identity (G±U versus A±C) and level of base modification (pseudouridine versus uridine). Co(NH3)63+ binding was observed with the four RNA hairpins that contained a G±U wobble pair in the stem region. ESI MS revealed 1:1 and 1:2 complex formation with all RNAs. Weaker binding was observed with the fifth RNA hairpin that contained an A±C wobble pair in the stem region. The effects of pH on Co(NH3)63+ binding were also examined." @default.
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- W1982118557 date "2006-10-01" @default.
- W1982118557 modified "2023-10-18" @default.
- W1982118557 title "Probing RNA hairpins with cobalt(III)hexammine and electrospray ionization mass spectrometry" @default.
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- W1982118557 doi "https://doi.org/10.1016/j.jasms.2006.07.006" @default.
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