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- W1982118863 abstract "ABSTRACT Streptococcus suis is an emerging zoonotic agent responsible for high-mortality outbreaks among the human population in China. In this species, the ABC transporter SatAB mediates fluoroquinolone resistance when overexpressed. Here, we describe and characterize satR , an open reading frame (ORF) encoding a MarR superfamily regulator that acts as a repressor of satAB. satR is cotranscribed with satAB , and its interruption entails the overexpression of the pump, leading to a clinically relevant increase in resistance to fluoroquinolones." @default.
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- W1982118863 date "2013-07-01" @default.
- W1982118863 modified "2023-10-14" @default.
- W1982118863 title "SatR Is a Repressor of Fluoroquinolone Efflux Pump SatAB" @default.
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- W1982118863 doi "https://doi.org/10.1128/aac.00515-13" @default.
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