Matches in SemOpenAlex for { <https://semopenalex.org/work/W1982119435> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W1982119435 endingPage "1389" @default.
- W1982119435 startingPage "1377" @default.
- W1982119435 abstract "1. The disposition and urinary metabolic pattern of 14C-cabergoline was studied in rat, monkey and man after oral administration of the labelled drug.2. In all species radioactivity was mainly excreted in faeces, with urinary excretion accounting for 11, 13 and 22% of the dose in rat, monkey and man, respectively.3. After oral treatment, biliary excretion of radioactivity in rat accounted for 19% of the dose within 24 h.4. Unchanged drug in 0-24-h urine samples of rat, monkey and man amounted to 20, 9 and 10% of urinary radioactivity, respectively. In the 24-72-h urine samples of all species the relative percentage of unchanged drug increased compared with that measured in the 0-24-h urine.5. The main metabolite was the acid derivative (FCE21589), which in 0-24-h urine samples of rat, monkey and man accounted for 30, 21 and 41% of urinary radioactivity, respectively.6. Other metabolites identified in urine of all species resulted from hydrolysis of the urea moiety, the loss of the 3-dimethylaminopropyl group and the deallylation of the piperidine nitrogen." @default.
- W1982119435 created "2016-06-24" @default.
- W1982119435 creator A5000096053 @default.
- W1982119435 creator A5003140724 @default.
- W1982119435 creator A5010091677 @default.
- W1982119435 creator A5043001457 @default.
- W1982119435 creator A5061967713 @default.
- W1982119435 creator A5063328267 @default.
- W1982119435 date "1993-01-01" @default.
- W1982119435 modified "2023-09-25" @default.
- W1982119435 title "Disposition and urinary metabolic pattern of cabergoline, a potent dopaminergic agonist, in rat, monkey and man" @default.
- W1982119435 cites W155804675 @default.
- W1982119435 cites W1966139877 @default.
- W1982119435 cites W1971440249 @default.
- W1982119435 cites W1975706451 @default.
- W1982119435 cites W1982582876 @default.
- W1982119435 cites W2001339171 @default.
- W1982119435 cites W2002198859 @default.
- W1982119435 cites W2031239996 @default.
- W1982119435 cites W2036485096 @default.
- W1982119435 cites W2052473125 @default.
- W1982119435 cites W2067147952 @default.
- W1982119435 cites W2074337014 @default.
- W1982119435 cites W2078885148 @default.
- W1982119435 cites W2083894069 @default.
- W1982119435 cites W2168782332 @default.
- W1982119435 cites W2170419349 @default.
- W1982119435 cites W2222235304 @default.
- W1982119435 cites W2308448970 @default.
- W1982119435 cites W2322521790 @default.
- W1982119435 cites W2323651970 @default.
- W1982119435 cites W2411827491 @default.
- W1982119435 cites W4206600246 @default.
- W1982119435 doi "https://doi.org/10.3109/00498259309059447" @default.
- W1982119435 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7907829" @default.
- W1982119435 hasPublicationYear "1993" @default.
- W1982119435 type Work @default.
- W1982119435 sameAs 1982119435 @default.
- W1982119435 citedByCount "15" @default.
- W1982119435 countsByYear W19821194352013 @default.
- W1982119435 countsByYear W19821194352019 @default.
- W1982119435 countsByYear W19821194352022 @default.
- W1982119435 crossrefType "journal-article" @default.
- W1982119435 hasAuthorship W1982119435A5000096053 @default.
- W1982119435 hasAuthorship W1982119435A5003140724 @default.
- W1982119435 hasAuthorship W1982119435A5010091677 @default.
- W1982119435 hasAuthorship W1982119435A5043001457 @default.
- W1982119435 hasAuthorship W1982119435A5061967713 @default.
- W1982119435 hasAuthorship W1982119435A5063328267 @default.
- W1982119435 hasConcept C10146269 @default.
- W1982119435 hasConcept C126322002 @default.
- W1982119435 hasConcept C134018914 @default.
- W1982119435 hasConcept C185592680 @default.
- W1982119435 hasConcept C2777056448 @default.
- W1982119435 hasConcept C2777477808 @default.
- W1982119435 hasConcept C2779064019 @default.
- W1982119435 hasConcept C2779832395 @default.
- W1982119435 hasConcept C2780026642 @default.
- W1982119435 hasConcept C71315377 @default.
- W1982119435 hasConcept C71924100 @default.
- W1982119435 hasConcept C77411442 @default.
- W1982119435 hasConcept C86803240 @default.
- W1982119435 hasConcept C98274493 @default.
- W1982119435 hasConceptScore W1982119435C10146269 @default.
- W1982119435 hasConceptScore W1982119435C126322002 @default.
- W1982119435 hasConceptScore W1982119435C134018914 @default.
- W1982119435 hasConceptScore W1982119435C185592680 @default.
- W1982119435 hasConceptScore W1982119435C2777056448 @default.
- W1982119435 hasConceptScore W1982119435C2777477808 @default.
- W1982119435 hasConceptScore W1982119435C2779064019 @default.
- W1982119435 hasConceptScore W1982119435C2779832395 @default.
- W1982119435 hasConceptScore W1982119435C2780026642 @default.
- W1982119435 hasConceptScore W1982119435C71315377 @default.
- W1982119435 hasConceptScore W1982119435C71924100 @default.
- W1982119435 hasConceptScore W1982119435C77411442 @default.
- W1982119435 hasConceptScore W1982119435C86803240 @default.
- W1982119435 hasConceptScore W1982119435C98274493 @default.
- W1982119435 hasIssue "12" @default.
- W1982119435 hasLocation W19821194351 @default.
- W1982119435 hasLocation W19821194352 @default.
- W1982119435 hasOpenAccess W1982119435 @default.
- W1982119435 hasPrimaryLocation W19821194351 @default.
- W1982119435 hasRelatedWork W2009543509 @default.
- W1982119435 hasRelatedWork W2045937169 @default.
- W1982119435 hasRelatedWork W2057381326 @default.
- W1982119435 hasRelatedWork W2066739959 @default.
- W1982119435 hasRelatedWork W2270196194 @default.
- W1982119435 hasRelatedWork W2273147184 @default.
- W1982119435 hasRelatedWork W2406801323 @default.
- W1982119435 hasRelatedWork W3214475116 @default.
- W1982119435 hasRelatedWork W797757511 @default.
- W1982119435 hasRelatedWork W1946186729 @default.
- W1982119435 hasVolume "23" @default.
- W1982119435 isParatext "false" @default.
- W1982119435 isRetracted "false" @default.
- W1982119435 magId "1982119435" @default.
- W1982119435 workType "article" @default.