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- W1982143310 abstract "Objective: To compare serum concentrations of risperidone, 9‐hydroxy (OH) risperidone and risperidone plus 9‐OH risperidone, as well as the 9‐OH risperidone/risperidone ratio in patients receiving depot and oral risperidone. Method: Serum concentrations from 78 patients receiving three different doses of risperidone depot were measured and compared with serum concentrations from 82 patients taking three different doses of oral risperidone. Results: Patients receiving risperidone depot had significantly lower serum concentrations of risperidone plus 9‐OH risperidone than patients taking oral risperidone. More interestingly, the 9‐OH risperidone/risperidone ratio was also significantly lower in patients receiving risperidone depot than in patients taking oral risperidone. Conclusion: Serum concentrations of risperidone plus 9‐OH risperidone may be a rather poor indication of the antipsychotic efficacy of risperidone unless their ratio is also considered." @default.
- W1982143310 created "2016-06-24" @default.
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- W1982143310 date "2006-06-07" @default.
- W1982143310 modified "2023-10-18" @default.
- W1982143310 title "Serum concentrations of risperidone and 9-OH risperidone following intramuscular injection of long-acting risperidone compared with oral risperidone medication" @default.
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- W1982143310 doi "https://doi.org/10.1111/j.1600-0447.2006.00840.x" @default.
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