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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1982163944> ?p ?o ?g. }

• W1982163944 endingPage "8331" @default.
• W1982163944 startingPage "8323" @default.
• W1982163944 abstract "A versatile synthesis of hydroxylated and epoxy 1-azepin 2-ones substituted at N1, C-3 and C-4 or C-7 has been developed. The sequence involves ring-closing metathesis of an amino acid derived diene amide, followed by either epoxidation or dihydroxylation, of the resulting alkene. Assay of the product epoxides (10, 18, 25) and diols (9a, 17, 24) against HIV protease reveals micromolar inhibition." @default.
• W1982163944 created "2016-06-24" @default.
• W1982163944 creator A5028019435 @default.
• W1982163944 creator A5033537928 @default.
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• W1982163944 date "2006-12-01" @default.
• W1982163944 modified "2023-10-09" @default.
• W1982163944 title "Synthesis of amino acid derived seven-membered lactams by RCM and their evaluation against HIV protease" @default.
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• W1982163944 doi "https://doi.org/10.1016/j.bmc.2006.09.009" @default.
• W1982163944 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17010620" @default.
• W1982163944 hasPublicationYear "2006" @default.
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