Matches in SemOpenAlex for { <https://semopenalex.org/work/W1982173313> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W1982173313 endingPage "254" @default.
- W1982173313 startingPage "251" @default.
- W1982173313 abstract "The intent of the study was to determine whether altering the metabolism of neurosteroids via blockade of the enzyme, steroid sulfatase, could enhance retention test performance in rats. The steroid sulfatase inhibitor estrone-3-O-sulfamate (EMATE) was administered alone and in combination with the neurosteroid dehydroepiandrosterone sulfate (DHEAS) to rats which were then tested for the reversal of scopolamine induced amnesia. EMATE enhanced the reversal of amnesia by DHEAS as measured by a passive avoidance test. When administered without DHEAS, as a single acute dose, EMATE had no effect. When administered without DHEAS over 10 consecutive days, however, EMATE significantly improved retention. These results suggest that steroid sulfatase inhibition can potentiate the memory enhancing properties of DHEAS. The study also suggests that increasing the levels of endogenous sulfated neurosteroids via the inhibition of steroid sulfatase activity may enhance learning and/or memory function." @default.
- W1982173313 created "2016-06-24" @default.
- W1982173313 creator A5009814059 @default.
- W1982173313 creator A5016934859 @default.
- W1982173313 creator A5040018415 @default.
- W1982173313 creator A5056383528 @default.
- W1982173313 date "1995-10-01" @default.
- W1982173313 modified "2023-09-26" @default.
- W1982173313 title "Reversal of scopolamine induced amnesia in rats by the steroid sulfatase inhibitor estrone-3-O-sulfamate" @default.
- W1982173313 cites W1504576116 @default.
- W1982173313 cites W1964427298 @default.
- W1982173313 cites W1991080894 @default.
- W1982173313 cites W2006442321 @default.
- W1982173313 cites W2020036669 @default.
- W1982173313 cites W2023572516 @default.
- W1982173313 cites W2026278465 @default.
- W1982173313 cites W2047218252 @default.
- W1982173313 cites W2055112994 @default.
- W1982173313 cites W2069223507 @default.
- W1982173313 cites W2087495709 @default.
- W1982173313 cites W4253189553 @default.
- W1982173313 doi "https://doi.org/10.1016/0926-6410(95)90016-0" @default.
- W1982173313 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8580738" @default.
- W1982173313 hasPublicationYear "1995" @default.
- W1982173313 type Work @default.
- W1982173313 sameAs 1982173313 @default.
- W1982173313 citedByCount "60" @default.
- W1982173313 countsByYear W19821733132012 @default.
- W1982173313 countsByYear W19821733132013 @default.
- W1982173313 countsByYear W19821733132014 @default.
- W1982173313 countsByYear W19821733132015 @default.
- W1982173313 crossrefType "journal-article" @default.
- W1982173313 hasAuthorship W1982173313A5009814059 @default.
- W1982173313 hasAuthorship W1982173313A5016934859 @default.
- W1982173313 hasAuthorship W1982173313A5040018415 @default.
- W1982173313 hasAuthorship W1982173313A5056383528 @default.
- W1982173313 hasConcept C118552586 @default.
- W1982173313 hasConcept C126322002 @default.
- W1982173313 hasConcept C134018914 @default.
- W1982173313 hasConcept C15744967 @default.
- W1982173313 hasConcept C168258287 @default.
- W1982173313 hasConcept C170493617 @default.
- W1982173313 hasConcept C185592680 @default.
- W1982173313 hasConcept C2776992908 @default.
- W1982173313 hasConcept C2777911890 @default.
- W1982173313 hasConcept C2778090324 @default.
- W1982173313 hasConcept C2778615406 @default.
- W1982173313 hasConcept C2780193516 @default.
- W1982173313 hasConcept C2780657110 @default.
- W1982173313 hasConcept C2780902042 @default.
- W1982173313 hasConcept C44796713 @default.
- W1982173313 hasConcept C71315377 @default.
- W1982173313 hasConcept C71924100 @default.
- W1982173313 hasConcept C98274493 @default.
- W1982173313 hasConceptScore W1982173313C118552586 @default.
- W1982173313 hasConceptScore W1982173313C126322002 @default.
- W1982173313 hasConceptScore W1982173313C134018914 @default.
- W1982173313 hasConceptScore W1982173313C15744967 @default.
- W1982173313 hasConceptScore W1982173313C168258287 @default.
- W1982173313 hasConceptScore W1982173313C170493617 @default.
- W1982173313 hasConceptScore W1982173313C185592680 @default.
- W1982173313 hasConceptScore W1982173313C2776992908 @default.
- W1982173313 hasConceptScore W1982173313C2777911890 @default.
- W1982173313 hasConceptScore W1982173313C2778090324 @default.
- W1982173313 hasConceptScore W1982173313C2778615406 @default.
- W1982173313 hasConceptScore W1982173313C2780193516 @default.
- W1982173313 hasConceptScore W1982173313C2780657110 @default.
- W1982173313 hasConceptScore W1982173313C2780902042 @default.
- W1982173313 hasConceptScore W1982173313C44796713 @default.
- W1982173313 hasConceptScore W1982173313C71315377 @default.
- W1982173313 hasConceptScore W1982173313C71924100 @default.
- W1982173313 hasConceptScore W1982173313C98274493 @default.
- W1982173313 hasIssue "4" @default.
- W1982173313 hasLocation W19821733131 @default.
- W1982173313 hasLocation W19821733132 @default.
- W1982173313 hasOpenAccess W1982173313 @default.
- W1982173313 hasPrimaryLocation W19821733131 @default.
- W1982173313 hasRelatedWork W1982173313 @default.
- W1982173313 hasRelatedWork W2063972305 @default.
- W1982173313 hasRelatedWork W2079893664 @default.
- W1982173313 hasRelatedWork W2089989561 @default.
- W1982173313 hasRelatedWork W2092034319 @default.
- W1982173313 hasRelatedWork W2149170691 @default.
- W1982173313 hasRelatedWork W2228194225 @default.
- W1982173313 hasRelatedWork W2430437650 @default.
- W1982173313 hasRelatedWork W3216893825 @default.
- W1982173313 hasRelatedWork W6311592 @default.
- W1982173313 hasVolume "2" @default.
- W1982173313 isParatext "false" @default.
- W1982173313 isRetracted "false" @default.
- W1982173313 magId "1982173313" @default.
- W1982173313 workType "article" @default.