Matches in SemOpenAlex for { <https://semopenalex.org/work/W1982173833> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W1982173833 abstract "Small animal diffuse optical tomography is an appealing tool for the investigation of molecular events in cancer research and drug developments. The combination of the functional information brought by an optical system and the anatomical information delivered by X-Rays enables i) a fast multimodality animal examination; ii) the correlation between the biodistribution of the molecular probes and the morphology of the animal; iii) a more accurate optical data reconstructions by using the anatomy of the animal as a constrain in the reconstructions. A small animal multimodality tomographer for the coregistration of fluorescence optical signals and X-rays measurements is used in the present study. The optical system is composed with a CW laser and a CCD camera coupled with an appropriate combination of filters for the fluorescence detection. The animal is placed inside a transparent tube filled with an index matching fluid. The X-ray generator and detector have been positioned perpendicularly to the optical chain. Original optical calibration techniques have been developed in order to control at any time the alignment between the incident beam, the axis of the cylinder and the focus plan of the CCD. Specific developments have also been handled for obtaining the geometry correlation between optical and X-rays data reconstructions. This experimental setup is used in the present work for a study conducted on different kinds of fluorochromes for the purpose of the development of new molecular probes. The instrument is also used for in vivo biological study conducted on mice bearing tumors in the lungs, and tagged with near infrared optical probes (targeting probes such as Transferin- AlexaFluor 750 or such as RAFT-(cRGD)<sub>4</sub>-Alexa700/Alexa750)." @default.
- W1982173833 created "2016-06-24" @default.
- W1982173833 creator A5000801262 @default.
- W1982173833 creator A5014358188 @default.
- W1982173833 creator A5047748552 @default.
- W1982173833 creator A5062620899 @default.
- W1982173833 creator A5071960307 @default.
- W1982173833 creator A5073299235 @default.
- W1982173833 date "2007-07-05" @default.
- W1982173833 modified "2023-09-25" @default.
- W1982173833 title "Whole body in vivo examination of small animals by simultaneous X-rays/optical tomography: comparison between the reconstructions obtained with different types of fluorescent labels" @default.
- W1982173833 cites W1985478993 @default.
- W1982173833 cites W1997006057 @default.
- W1982173833 cites W2017566393 @default.
- W1982173833 cites W2017712289 @default.
- W1982173833 cites W2037521346 @default.
- W1982173833 cites W2051383565 @default.
- W1982173833 cites W2089499666 @default.
- W1982173833 cites W2106203321 @default.
- W1982173833 cites W2112464550 @default.
- W1982173833 cites W2157812230 @default.
- W1982173833 doi "https://doi.org/10.1117/12.728373" @default.
- W1982173833 hasPublicationYear "2007" @default.
- W1982173833 type Work @default.
- W1982173833 sameAs 1982173833 @default.
- W1982173833 citedByCount "2" @default.
- W1982173833 crossrefType "proceedings-article" @default.
- W1982173833 hasAuthorship W1982173833A5000801262 @default.
- W1982173833 hasAuthorship W1982173833A5014358188 @default.
- W1982173833 hasAuthorship W1982173833A5047748552 @default.
- W1982173833 hasAuthorship W1982173833A5062620899 @default.
- W1982173833 hasAuthorship W1982173833A5071960307 @default.
- W1982173833 hasAuthorship W1982173833A5073299235 @default.
- W1982173833 hasConcept C120665830 @default.
- W1982173833 hasConcept C121332964 @default.
- W1982173833 hasConcept C136229726 @default.
- W1982173833 hasConcept C136339569 @default.
- W1982173833 hasConcept C145417883 @default.
- W1982173833 hasConcept C150903083 @default.
- W1982173833 hasConcept C163716698 @default.
- W1982173833 hasConcept C192562407 @default.
- W1982173833 hasConcept C207001950 @default.
- W1982173833 hasConcept C2777413408 @default.
- W1982173833 hasConcept C2777807558 @default.
- W1982173833 hasConcept C41008148 @default.
- W1982173833 hasConcept C520434653 @default.
- W1982173833 hasConcept C71924100 @default.
- W1982173833 hasConcept C86803240 @default.
- W1982173833 hasConcept C94915269 @default.
- W1982173833 hasConceptScore W1982173833C120665830 @default.
- W1982173833 hasConceptScore W1982173833C121332964 @default.
- W1982173833 hasConceptScore W1982173833C136229726 @default.
- W1982173833 hasConceptScore W1982173833C136339569 @default.
- W1982173833 hasConceptScore W1982173833C145417883 @default.
- W1982173833 hasConceptScore W1982173833C150903083 @default.
- W1982173833 hasConceptScore W1982173833C163716698 @default.
- W1982173833 hasConceptScore W1982173833C192562407 @default.
- W1982173833 hasConceptScore W1982173833C207001950 @default.
- W1982173833 hasConceptScore W1982173833C2777413408 @default.
- W1982173833 hasConceptScore W1982173833C2777807558 @default.
- W1982173833 hasConceptScore W1982173833C41008148 @default.
- W1982173833 hasConceptScore W1982173833C520434653 @default.
- W1982173833 hasConceptScore W1982173833C71924100 @default.
- W1982173833 hasConceptScore W1982173833C86803240 @default.
- W1982173833 hasConceptScore W1982173833C94915269 @default.
- W1982173833 hasLocation W19821738331 @default.
- W1982173833 hasOpenAccess W1982173833 @default.
- W1982173833 hasPrimaryLocation W19821738331 @default.
- W1982173833 hasRelatedWork W1596394325 @default.
- W1982173833 hasRelatedWork W1974752953 @default.
- W1982173833 hasRelatedWork W1988302262 @default.
- W1982173833 hasRelatedWork W1993612264 @default.
- W1982173833 hasRelatedWork W2007798619 @default.
- W1982173833 hasRelatedWork W2045925106 @default.
- W1982173833 hasRelatedWork W2073776015 @default.
- W1982173833 hasRelatedWork W2991543261 @default.
- W1982173833 hasRelatedWork W3028162090 @default.
- W1982173833 hasRelatedWork W181650390 @default.
- W1982173833 isParatext "false" @default.
- W1982173833 isRetracted "false" @default.
- W1982173833 magId "1982173833" @default.
- W1982173833 workType "article" @default.