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- W1982182476 abstract "It has previously been demonstrated that newborn infants are capable of responding to change of posture and insulin hypoglycemia with. an increase in catecholamine excretion. Similarly, previous studies by other workers have shown that severe anoxia, at least, evokes a marked release of catecholamines in animals. When newborn infants were exposed for 15 minutes to a gas mixture containing 15.5% oxygen and 84.5% nitrogen, no significant change in the urinary excretion of noradrenaline and adrenaline ensued. This would suggest that either the newborn is incapable of responding to this stimulus with an increase in catecholamine excretion or the stimulus itself is not of sufficient severity to produce such a response. In either case, any physiologic response in newborns following exposure to a hypoxic mixture of this degree, would then be mediated by mechanisms other than catecholamine release. The study also suggests, however, that increasing postnatal age exhibits a positive correlation with the response to the hypoxic stimulus used, in terms of increases in noradrenaline excretion. The validity of these findings as well as their significance must await confirmatory studies. Dopamine was found to be present in the urine of newborn infants in amounts roughly nine times that of noradrenaline, a ratio parallel to that observed by others for adults. No correlation between the hypoxic stimulus and dopamine excretion was found. The present confusion concerning the significance of dopamine, in both urine and tissues, is briefly reviewed." @default.
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- W1982182476 date "1961-09-01" @default.
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- W1982182476 title "Catecholamine Excretion in the Newborn Period: Effect of Short Periods of Induced Hypoxial" @default.
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- W1982182476 doi "https://doi.org/10.1111/j.1651-2227.1961.tb08205.x" @default.
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