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- W1982210010 abstract "To study the involvement of cholesterol esters in myelination and demyelination, we determined the concentration of free cholesterol and cholesterol esters and the activity of hydrolytic cholesterol esterase (sterol ester hydrolase; EC 3.1.1.13) in hen sciatic nerve during Wallerian degeneration. A progressive increase in the ratio of cholesterol ester to free cholesterol was observed in the degenerating nerve at 8, 16 and 32 days after nerve section. Hydrolytic cholesterol esterase activity decreased progressively in the degenerating nerves at the same time. In addition we measured the ratio of RNA to DNA, and the activity of the NADP+-dependent isocitrate dehydrogenase [L8-isocitrate: NADP oxidoreductase (decarboxylating); EC 1.1.1.42] at 8, 16 and 32 days after nerve section. The RNA to DNA ratios decreased progressively in the degenerating nerves. NADP+-dependent isocitrate dehydrogenase increased in activity after nerve section, reaching a peak at 16 days." @default.
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- W1982210010 date "1970-08-01" @default.
- W1982210010 modified "2023-09-29" @default.
- W1982210010 title "CHOLESTEROL ESTERS AND HYDROLYTIC CHOLESTEROL ESTERASE DURING WALLERIAN DEGENERATION" @default.
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- W1982210010 doi "https://doi.org/10.1111/j.1471-4159.1970.tb03364.x" @default.
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