Matches in SemOpenAlex for { <https://semopenalex.org/work/W1982335331> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W1982335331 endingPage "160" @default.
- W1982335331 startingPage "155" @default.
- W1982335331 abstract "Activation-induced cytidine deaminase (AID) is an enzyme that catalyzes somatic hypermutation (SHM) and class switch recombination (CSR) of the immunoglobulin (Ig) gene. The expression of AID was reported to be confined to the germinal center (GC). Burkitt lymphoma (BL) cells are regarded as being derived from GC cells. BL cells have been reported to have SHM in the Ig gene with variety in terms of degree, antigen selection and ongoing mutation characteristic. We investigated the expression of AID in 15 BL cell lines by RT-PCR. In only 2 BL cell lines, Tree92 and Black93, AID expression was not detected, and the IgVH gene of these 2 cell lines was not mutated. Tree92 expresses terminal deoxy-nucleotidyl transferase (TdT) and recombination activating gene (RAG)1, but Black93 does not, as is typical of the BL phenotype. BL cells are generally derived from GC B-cell expressing AID, but are rarely derived from the stage of B-lineage differentiation in which AID is not yet expressed, causing the absence of mutation in the IgVH." @default.
- W1982335331 created "2016-06-24" @default.
- W1982335331 creator A5003271349 @default.
- W1982335331 creator A5004776824 @default.
- W1982335331 creator A5029191285 @default.
- W1982335331 creator A5032051871 @default.
- W1982335331 creator A5073205330 @default.
- W1982335331 creator A5075789250 @default.
- W1982335331 creator A5076728997 @default.
- W1982335331 creator A5087489183 @default.
- W1982335331 creator A5091266271 @default.
- W1982335331 date "2004-01-01" @default.
- W1982335331 modified "2023-10-11" @default.
- W1982335331 title "Expression of Activation-Induced Cytidine Deaminase (AID) in Burkitt Lymphoma Cells: Rare AID-Negative Cell Lines with the Unmutated Rearranged V<sub>H</sub>Gene" @default.
- W1982335331 cites W2060983388 @default.
- W1982335331 cites W2139968053 @default.
- W1982335331 cites W2141308574 @default.
- W1982335331 doi "https://doi.org/10.1080/1042819031000139701" @default.
- W1982335331 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15061213" @default.
- W1982335331 hasPublicationYear "2004" @default.
- W1982335331 type Work @default.
- W1982335331 sameAs 1982335331 @default.
- W1982335331 citedByCount "14" @default.
- W1982335331 countsByYear W19823353312012 @default.
- W1982335331 countsByYear W19823353312013 @default.
- W1982335331 countsByYear W19823353312014 @default.
- W1982335331 countsByYear W19823353312017 @default.
- W1982335331 crossrefType "journal-article" @default.
- W1982335331 hasAuthorship W1982335331A5003271349 @default.
- W1982335331 hasAuthorship W1982335331A5004776824 @default.
- W1982335331 hasAuthorship W1982335331A5029191285 @default.
- W1982335331 hasAuthorship W1982335331A5032051871 @default.
- W1982335331 hasAuthorship W1982335331A5073205330 @default.
- W1982335331 hasAuthorship W1982335331A5075789250 @default.
- W1982335331 hasAuthorship W1982335331A5076728997 @default.
- W1982335331 hasAuthorship W1982335331A5087489183 @default.
- W1982335331 hasAuthorship W1982335331A5091266271 @default.
- W1982335331 hasConcept C104317684 @default.
- W1982335331 hasConcept C128526571 @default.
- W1982335331 hasConcept C137756551 @default.
- W1982335331 hasConcept C153911025 @default.
- W1982335331 hasConcept C154113507 @default.
- W1982335331 hasConcept C159654299 @default.
- W1982335331 hasConcept C190283241 @default.
- W1982335331 hasConcept C196795494 @default.
- W1982335331 hasConcept C27082348 @default.
- W1982335331 hasConcept C2776985229 @default.
- W1982335331 hasConcept C2778453870 @default.
- W1982335331 hasConcept C2992511266 @default.
- W1982335331 hasConcept C3020196193 @default.
- W1982335331 hasConcept C54355233 @default.
- W1982335331 hasConcept C81885089 @default.
- W1982335331 hasConcept C86803240 @default.
- W1982335331 hasConcept C96926380 @default.
- W1982335331 hasConceptScore W1982335331C104317684 @default.
- W1982335331 hasConceptScore W1982335331C128526571 @default.
- W1982335331 hasConceptScore W1982335331C137756551 @default.
- W1982335331 hasConceptScore W1982335331C153911025 @default.
- W1982335331 hasConceptScore W1982335331C154113507 @default.
- W1982335331 hasConceptScore W1982335331C159654299 @default.
- W1982335331 hasConceptScore W1982335331C190283241 @default.
- W1982335331 hasConceptScore W1982335331C196795494 @default.
- W1982335331 hasConceptScore W1982335331C27082348 @default.
- W1982335331 hasConceptScore W1982335331C2776985229 @default.
- W1982335331 hasConceptScore W1982335331C2778453870 @default.
- W1982335331 hasConceptScore W1982335331C2992511266 @default.
- W1982335331 hasConceptScore W1982335331C3020196193 @default.
- W1982335331 hasConceptScore W1982335331C54355233 @default.
- W1982335331 hasConceptScore W1982335331C81885089 @default.
- W1982335331 hasConceptScore W1982335331C86803240 @default.
- W1982335331 hasConceptScore W1982335331C96926380 @default.
- W1982335331 hasIssue "1" @default.
- W1982335331 hasLocation W19823353311 @default.
- W1982335331 hasLocation W19823353312 @default.
- W1982335331 hasOpenAccess W1982335331 @default.
- W1982335331 hasPrimaryLocation W19823353311 @default.
- W1982335331 hasRelatedWork W115126346 @default.
- W1982335331 hasRelatedWork W1985389664 @default.
- W1982335331 hasRelatedWork W2000335629 @default.
- W1982335331 hasRelatedWork W2016165485 @default.
- W1982335331 hasRelatedWork W2024426483 @default.
- W1982335331 hasRelatedWork W2043870412 @default.
- W1982335331 hasRelatedWork W2086291721 @default.
- W1982335331 hasRelatedWork W2094097491 @default.
- W1982335331 hasRelatedWork W2165608602 @default.
- W1982335331 hasRelatedWork W8809098 @default.
- W1982335331 hasVolume "45" @default.
- W1982335331 isParatext "false" @default.
- W1982335331 isRetracted "false" @default.
- W1982335331 magId "1982335331" @default.
- W1982335331 workType "article" @default.