Matches in SemOpenAlex for { <https://semopenalex.org/work/W1982353176> ?p ?o ?g. }
- W1982353176 endingPage "1130" @default.
- W1982353176 startingPage "1121" @default.
- W1982353176 abstract "This study was designed to investigate (a) the presence of protein gene product 9.5 (PGP 9.5), ubiquitin, and neuropeptide Y (NPY) in the neuroendocrine and secretory epithelium of the human normal prostate and its secretions, and (b) the changes in immunoreactivity to these proteins in men with benign prostatic hyperplasia. Western blotting and light microscopic immunohistochemistry techniques were used and the numerical density of immunoreactive neuroendocrine cells, and the volume fractions of immunostained secretory epithelium were evaluated. Western blotting revealed the presence of the three antigens in both tissue homogenates and prostate secretion. Some neuroendocrine cells immunoreacted to PGP 9.5 and NPY in all the prostate regions of control specimens. Ubiquitin immunoreactivity was detected in the nuclei from both basal cells and secretory epithelial cells. The cytoplasm of the secretory cells and the glandular lumen also showed immunostaining for the three proteins. The numerical densities of both PGP 9.5 and NPY neuroendocrine cells were lower in hyperplasia than in controls. No differences in the volume fraction occupied by epithelial immunostaining to both proteins was found between hyperplastic and control prostates. We concluded that (a) PGP 9.5 and NPY, but not ubiquitin, are common antigens in both neuroendocrine and secretory prostate cells, (b) the three immunoreactive proteins contribute to the prostate secretions, and (c) the secretion of ubiquitin is markedly diminished in the hyperplastic epithelium.(J Histochem Cytochem 48:1121-1130, 2000)" @default.
- W1982353176 created "2016-06-24" @default.
- W1982353176 creator A5003215527 @default.
- W1982353176 creator A5006990926 @default.
- W1982353176 creator A5008249764 @default.
- W1982353176 creator A5018758382 @default.
- W1982353176 creator A5049826457 @default.
- W1982353176 creator A5050324239 @default.
- W1982353176 creator A5061078993 @default.
- W1982353176 creator A5079298859 @default.
- W1982353176 creator A5088768411 @default.
- W1982353176 date "2000-08-01" @default.
- W1982353176 modified "2023-10-16" @default.
- W1982353176 title "Immunohistochemical Localization of Protein Gene Product 9.5, Ubiquitin, and Neuropeptide Y Immunoreactivities in Epithelial and Neuroendocrine Cells from Normal and Hyperplastic Human Prostate" @default.
- W1982353176 cites W1495218540 @default.
- W1982353176 cites W1967573239 @default.
- W1982353176 cites W1972422736 @default.
- W1982353176 cites W1985850221 @default.
- W1982353176 cites W1991101546 @default.
- W1982353176 cites W1994351535 @default.
- W1982353176 cites W2003004392 @default.
- W1982353176 cites W2003784766 @default.
- W1982353176 cites W2015500761 @default.
- W1982353176 cites W2019556865 @default.
- W1982353176 cites W2020146120 @default.
- W1982353176 cites W2031887004 @default.
- W1982353176 cites W2032265042 @default.
- W1982353176 cites W2041110973 @default.
- W1982353176 cites W2042587614 @default.
- W1982353176 cites W2047834152 @default.
- W1982353176 cites W2051912465 @default.
- W1982353176 cites W2053807193 @default.
- W1982353176 cites W2054808365 @default.
- W1982353176 cites W2060572283 @default.
- W1982353176 cites W2070148039 @default.
- W1982353176 cites W2075092404 @default.
- W1982353176 cites W2076770926 @default.
- W1982353176 cites W2080295220 @default.
- W1982353176 cites W2086251495 @default.
- W1982353176 cites W2090612180 @default.
- W1982353176 cites W2100837269 @default.
- W1982353176 cites W2101108802 @default.
- W1982353176 cites W2105536309 @default.
- W1982353176 cites W2106875648 @default.
- W1982353176 cites W2137949869 @default.
- W1982353176 cites W2144595951 @default.
- W1982353176 cites W2145302607 @default.
- W1982353176 cites W2160481013 @default.
- W1982353176 cites W2167031568 @default.
- W1982353176 cites W2216870060 @default.
- W1982353176 cites W2288859182 @default.
- W1982353176 cites W2317646129 @default.
- W1982353176 cites W2327000334 @default.
- W1982353176 cites W2423393228 @default.
- W1982353176 cites W2473697229 @default.
- W1982353176 cites W82299136 @default.
- W1982353176 cites W85141871 @default.
- W1982353176 doi "https://doi.org/10.1177/002215540004800809" @default.
- W1982353176 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10898805" @default.
- W1982353176 hasPublicationYear "2000" @default.
- W1982353176 type Work @default.
- W1982353176 sameAs 1982353176 @default.
- W1982353176 citedByCount "30" @default.
- W1982353176 countsByYear W19823531762012 @default.
- W1982353176 countsByYear W19823531762017 @default.
- W1982353176 countsByYear W19823531762020 @default.
- W1982353176 countsByYear W19823531762021 @default.
- W1982353176 countsByYear W19823531762022 @default.
- W1982353176 countsByYear W19823531762023 @default.
- W1982353176 crossrefType "journal-article" @default.
- W1982353176 hasAuthorship W1982353176A5003215527 @default.
- W1982353176 hasAuthorship W1982353176A5006990926 @default.
- W1982353176 hasAuthorship W1982353176A5008249764 @default.
- W1982353176 hasAuthorship W1982353176A5018758382 @default.
- W1982353176 hasAuthorship W1982353176A5049826457 @default.
- W1982353176 hasAuthorship W1982353176A5050324239 @default.
- W1982353176 hasAuthorship W1982353176A5061078993 @default.
- W1982353176 hasAuthorship W1982353176A5079298859 @default.
- W1982353176 hasAuthorship W1982353176A5088768411 @default.
- W1982353176 hasBestOaLocation W19823531761 @default.
- W1982353176 hasConcept C121608353 @default.
- W1982353176 hasConcept C126322002 @default.
- W1982353176 hasConcept C134018914 @default.
- W1982353176 hasConcept C142724271 @default.
- W1982353176 hasConcept C203014093 @default.
- W1982353176 hasConcept C204232928 @default.
- W1982353176 hasConcept C2776235491 @default.
- W1982353176 hasConcept C2777562237 @default.
- W1982353176 hasConcept C2777858994 @default.
- W1982353176 hasConcept C4224716 @default.
- W1982353176 hasConcept C529295009 @default.
- W1982353176 hasConcept C54355233 @default.
- W1982353176 hasConcept C71924100 @default.
- W1982353176 hasConcept C77231918 @default.
- W1982353176 hasConcept C86803240 @default.
- W1982353176 hasConceptScore W1982353176C121608353 @default.
- W1982353176 hasConceptScore W1982353176C126322002 @default.
- W1982353176 hasConceptScore W1982353176C134018914 @default.