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- W1982360410 abstract "Cytochrome-c oxidase proteoliposomes containing internally trapped cytochrome c can turn over on internal or external cytochrome c. At low TMPD levels the internal activity is significantly lower than the external activity as the functional internal cytochrome c is not fully reduced in the steady state. Increasing TMPD concentration increases the internal rate to equal that of the external enzyme. Internal activity results in the accumulation of TMPD+. Valinomycin increases this accumulation and subsequently FCCP decreases it. In the presence of excess external cytochrome c, the effects of these ionophores are reversed. The internally-facing enzyme is thus capable of generating a ΔμH+ in proteoliposomes as well as in submitochondrial particles." @default.
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- W1982360410 date "1987-10-19" @default.
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- W1982360410 title "Activity of proteoliposomes containing cytochrome oxidase in the submitochondrial orientation" @default.
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- W1982360410 doi "https://doi.org/10.1016/0014-5793(87)80527-6" @default.
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