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- W1982384451 abstract "s 239 patients with diabetes and C. difficile colitis. Admission APACHE 2 scores were calculated. Results: During a period of 2 months there were 20 inpatients that had a diagnosis of C. difficile colitis with diabetes. There were 8 males and 12 females in the study cohort. The mean age (6SD) was 69.46 12.6 years with a mean (6SD) length of hospital stay of 12.26 11.7 days. On assessing the factors associated with an increased length of stay, statin use was inversely correlated with length of hospital stay (P 5 .06). On multivariate analysis, adjusting for insulin use, age and APACHE 2 scores, statin use (P 5 .04) was the only factor which was significantly associated with a decreased length of hospital stay in diabetic patients withC. difficile infection. According to the American Association of Endocrinologist guidelines for treating diabetes; aggressive management of dyslipidemia is critical with statins being the pharmacological treatment of choice (Grade A recommendationAACEguidelines) In this study cohort, only about 50% of the patients were on statins; though only 30% of the patients had a baseline LDL less than 70 mg/dL. Conclusions: Though this study has a small sample size, it doeshighlight the associationof statin use anddecreased length of hospital stay in diabetic patients with C. difficile infection. This study emphasizes the importance of aggressive use of statins in diabetics which may help in reducing economic burden and improving patient quality of life. Larger prospective studies are needed to confirm this beneficial association." @default.
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- W1982384451 date "2011-05-01" @default.
- W1982384451 modified "2023-09-25" @default.
- W1982384451 title "Extended Release Niacin/Laropiprant Lowers Atherogenic Lipids Across Patient Subgroups" @default.
- W1982384451 doi "https://doi.org/10.1016/j.jacl.2011.03.074" @default.
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