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• W1982440752 startingPage "21" @default.
• W1982440752 abstract "With close genomic and phenotypic similarity to humans, nonhuman primate models provide comprehensive epigenetic mimics of polycystic ovary syndrome (PCOS), suggesting early life targeting for prevention. Fetal exposure to testosterone (T), of all nonhuman primate emulations, provides the closest PCOS-like phenotypes, with early-to-mid gestation T-exposed female rhesus monkeys exhibiting adult reproductive, endocrinological and metabolic dysfunctional traits that are co-pathologies of PCOS. Late gestational T exposure, while inducing adult ovarian hyperandrogenism and menstrual abnormalities, has less dysfunctional metabolic accompaniment. Fetal exposures to dihydrotestosterone (DHT) or diethylstilbestrol (DES) suggest androgenic and estrogenic aspects of fetal programming. Neonatal exposure to T produces no PCOS-like outcome, while continuous T treatment of juvenile females causes precocious weight gain and early menarche (high T), or high LH and weight gain (moderate T). Acute T exposure of adult females generates polyfollicular ovaries, while chronic T exposure induces subtle menstrual irregularities without metabolic dysfunction." @default.
• W1982440752 created "2016-06-24" @default.
• W1982440752 creator A5014769599 @default.
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• W1982440752 creator A5083253733 @default.
• W1982440752 creator A5089718840 @default.
• W1982440752 date "2013-07-01" @default.
• W1982440752 modified "2023-09-28" @default.
• W1982440752 title "Nonhuman primate models of polycystic ovary syndrome" @default.
• W1982440752 cites W1162931128 @default.
• W1982440752 cites W1611301211 @default.
• W1982440752 cites W1885156792 @default.
• W1982440752 cites W1898114459 @default.
• W1982440752 cites W1964710334 @default.
• W1982440752 cites W1965402814 @default.
• W1982440752 cites W1966132436 @default.
• W1982440752 cites W1966937086 @default.
• W1982440752 cites W1967564560 @default.
• W1982440752 cites W1968248461 @default.
• W1982440752 cites W1969243517 @default.
• W1982440752 cites W1969893155 @default.
• W1982440752 cites W1969906376 @default.
• W1982440752 cites W1972008706 @default.
• W1982440752 cites W1975390269 @default.
• W1982440752 cites W1977681402 @default.
• W1982440752 cites W1993055761 @default.
• W1982440752 cites W1997029279 @default.
• W1982440752 cites W1997598121 @default.
• W1982440752 cites W2001088624 @default.
• W1982440752 cites W2001984895 @default.
• W1982440752 cites W2002130830 @default.
• W1982440752 cites W2003891399 @default.
• W1982440752 cites W2010946386 @default.
• W1982440752 cites W2014698814 @default.
• W1982440752 cites W2017534120 @default.
• W1982440752 cites W2019044441 @default.
• W1982440752 cites W2019771529 @default.
• W1982440752 cites W2021746404 @default.
• W1982440752 cites W2021881867 @default.
• W1982440752 cites W2023205015 @default.
• W1982440752 cites W2032313252 @default.
• W1982440752 cites W2036415561 @default.
• W1982440752 cites W2038052856 @default.
• W1982440752 cites W2040600141 @default.
• W1982440752 cites W2046452752 @default.
• W1982440752 cites W2051894323 @default.
• W1982440752 cites W2052785258 @default.
• W1982440752 cites W2054348561 @default.
• W1982440752 cites W2056645812 @default.
• W1982440752 cites W2060880891 @default.
• W1982440752 cites W2061189220 @default.
• W1982440752 cites W2061564642 @default.
• W1982440752 cites W2065788149 @default.
• W1982440752 cites W2068224022 @default.
• W1982440752 cites W2068597091 @default.
• W1982440752 cites W2069834447 @default.
• W1982440752 cites W2072345165 @default.
• W1982440752 cites W2074129937 @default.
• W1982440752 cites W2076208069 @default.
• W1982440752 cites W2077064783 @default.
• W1982440752 cites W2078094750 @default.
• W1982440752 cites W2079472989 @default.
• W1982440752 cites W2081095883 @default.
• W1982440752 cites W2081648314 @default.
• W1982440752 cites W2083441995 @default.
• W1982440752 cites W2087951293 @default.
• W1982440752 cites W2089211374 @default.
• W1982440752 cites W2089589494 @default.
• W1982440752 cites W2095078013 @default.
• W1982440752 cites W2096535752 @default.
• W1982440752 cites W2096972287 @default.
• W1982440752 cites W2099511866 @default.
• W1982440752 cites W2101045687 @default.
• W1982440752 cites W2102318195 @default.
• W1982440752 cites W2103732683 @default.
• W1982440752 cites W2105749473 @default.
• W1982440752 cites W2106213718 @default.
• W1982440752 cites W2107065593 @default.
• W1982440752 cites W2114124243 @default.
• W1982440752 cites W2114291118 @default.
• W1982440752 cites W2117110805 @default.
• W1982440752 cites W2117532854 @default.
• W1982440752 cites W2118848273 @default.
• W1982440752 cites W2121081996 @default.
• W1982440752 cites W2121877521 @default.
• W1982440752 cites W2123009569 @default.
• W1982440752 cites W2123592027 @default.
• W1982440752 cites W2123874077 @default.
• W1982440752 cites W2124074195 @default.
• W1982440752 cites W2125121954 @default.
• W1982440752 cites W2125529814 @default.
• W1982440752 cites W2125548284 @default.
• W1982440752 cites W2125717115 @default.
• W1982440752 cites W2126781372 @default.
• W1982440752 cites W2128186383 @default.
• W1982440752 cites W2130671816 @default.

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