FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1982449265> ?p ?o ?g. }

• W1982449265 endingPage "1052" @default.
• W1982449265 startingPage "1041" @default.
• W1982449265 abstract "Abstract In this study, we report the effects of acidic to basic residue point mutations (5K) on the dipole moment of RNAse SA at different pHs. Dipole moments were determined by measuring solution capacitance of the wild type (WT) and the 5K mutant with an impedance analyzer. The dipole moments were then (1) compared with theoretically calculated dipole moments, (2) analyzed to determine the effect of the point mutations, and (3) analyzed for their contribution to overall protein–protein interactions (PPI) in solution as quantitated by experimentally derived second virial coefficients. We determined that experimental and calculated dipoles were in reasonable agreement. Differences are likely due to local motions of residue side chains, which are not accounted for by the calculated dipole. We observed that the proteins' dipole moments increase as the pH is shifted further from their isoelectric points and that the wild‐type dipole moments were greater than those of the 5K. This is likely due to an increase in the proportion of one charge (either negative or positive) relative to the other. A greater charge disparity corresponded to a larger dipole moment. Finally, the larger dipole moments of the WT resulted in greater attractive overall PPI for that protein as compared to the 5K. Proteins 2011; © 2011 Wiley Periodicals, Inc." @default.
• W1982449265 created "2016-06-24" @default.
• W1982449265 creator A5011149614 @default.
• W1982449265 creator A5014092506 @default.
• W1982449265 creator A5046925288 @default.
• W1982449265 creator A5052883024 @default.
• W1982449265 creator A5053289468 @default.
• W1982449265 date "2011-12-28" @default.
• W1982449265 modified "2023-10-18" @default.
• W1982449265 title "Determination of the dipole moments of RNAse SA wild type and a basic mutant" @default.
• W1982449265 cites W1964510096 @default.
• W1982449265 cites W1969214182 @default.
• W1982449265 cites W1976805645 @default.
• W1982449265 cites W1978793609 @default.
• W1982449265 cites W1980188412 @default.
• W1982449265 cites W1987897323 @default.
• W1982449265 cites W2013434706 @default.
• W1982449265 cites W2024064076 @default.
• W1982449265 cites W2024716123 @default.
• W1982449265 cites W2026039351 @default.
• W1982449265 cites W2029582401 @default.
• W1982449265 cites W2029667189 @default.
• W1982449265 cites W2032117208 @default.
• W1982449265 cites W2032527102 @default.
• W1982449265 cites W2047399603 @default.
• W1982449265 cites W2047608438 @default.
• W1982449265 cites W2056213930 @default.
• W1982449265 cites W2057204174 @default.
• W1982449265 cites W2057263702 @default.
• W1982449265 cites W2058198758 @default.
• W1982449265 cites W2060085692 @default.
• W1982449265 cites W2076790509 @default.
• W1982449265 cites W2077936377 @default.
• W1982449265 cites W2086481000 @default.
• W1982449265 cites W2096324068 @default.
• W1982449265 cites W2096601751 @default.
• W1982449265 cites W2097618830 @default.
• W1982449265 cites W2106401765 @default.
• W1982449265 cites W2116210364 @default.
• W1982449265 cites W2127578051 @default.
• W1982449265 cites W2127697325 @default.
• W1982449265 cites W2142872302 @default.
• W1982449265 cites W2152997175 @default.
• W1982449265 cites W2160982787 @default.
• W1982449265 cites W2162166182 @default.
• W1982449265 cites W2218035893 @default.
• W1982449265 cites W2313147148 @default.
• W1982449265 cites W2333713376 @default.
• W1982449265 cites W4231466358 @default.
• W1982449265 cites W4238520503 @default.
• W1982449265 doi "https://doi.org/10.1002/prot.24006" @default.
• W1982449265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22213585" @default.
• W1982449265 hasPublicationYear "2011" @default.
• W1982449265 type Work @default.
• W1982449265 sameAs 1982449265 @default.
• W1982449265 citedByCount "7" @default.
• W1982449265 countsByYear W19824492652014 @default.
• W1982449265 countsByYear W19824492652017 @default.
• W1982449265 countsByYear W19824492652020 @default.
• W1982449265 countsByYear W19824492652022 @default.
• W1982449265 crossrefType "journal-article" @default.
• W1982449265 hasAuthorship W1982449265A5011149614 @default.
• W1982449265 hasAuthorship W1982449265A5014092506 @default.
• W1982449265 hasAuthorship W1982449265A5046925288 @default.
• W1982449265 hasAuthorship W1982449265A5052883024 @default.
• W1982449265 hasAuthorship W1982449265A5053289468 @default.
• W1982449265 hasConcept C104317684 @default.
• W1982449265 hasConcept C10879258 @default.
• W1982449265 hasConcept C121332964 @default.
• W1982449265 hasConcept C162120991 @default.
• W1982449265 hasConcept C173523689 @default.
• W1982449265 hasConcept C178790620 @default.
• W1982449265 hasConcept C179254644 @default.
• W1982449265 hasConcept C181199279 @default.
• W1982449265 hasConcept C184779094 @default.
• W1982449265 hasConcept C185592680 @default.
• W1982449265 hasConcept C198990423 @default.
• W1982449265 hasConcept C40899509 @default.
• W1982449265 hasConcept C41999313 @default.
• W1982449265 hasConcept C55493867 @default.
• W1982449265 hasConcept C62520636 @default.
• W1982449265 hasConcept C67705224 @default.
• W1982449265 hasConcept C96294017 @default.
• W1982449265 hasConceptScore W1982449265C104317684 @default.
• W1982449265 hasConceptScore W1982449265C10879258 @default.
• W1982449265 hasConceptScore W1982449265C121332964 @default.
• W1982449265 hasConceptScore W1982449265C162120991 @default.
• W1982449265 hasConceptScore W1982449265C173523689 @default.
• W1982449265 hasConceptScore W1982449265C178790620 @default.
• W1982449265 hasConceptScore W1982449265C179254644 @default.
• W1982449265 hasConceptScore W1982449265C181199279 @default.
• W1982449265 hasConceptScore W1982449265C184779094 @default.
• W1982449265 hasConceptScore W1982449265C185592680 @default.
• W1982449265 hasConceptScore W1982449265C198990423 @default.
• W1982449265 hasConceptScore W1982449265C40899509 @default.
• W1982449265 hasConceptScore W1982449265C41999313 @default.
• W1982449265 hasConceptScore W1982449265C55493867 @default.
• W1982449265 hasConceptScore W1982449265C62520636 @default.

• next