FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1982462300> ?p ?o ?g. }

• W1982462300 endingPage "313" @default.
• W1982462300 startingPage "302" @default.
• W1982462300 abstract "Numerous studies have demonstrated a critical role for T cell avidity in predicting in vivo efficacy. Even though the measurement of avidity is now a routine assessment for the analysis of effector and memory T cell populations, our understanding of how this property is controlled in vivo at both the population and individual cell levels is limited. Our previous studies have identified high avidity as a property of the initial effector population generated in mice following respiratory virus infection. As the response progresses, lower avidity cells appear in the effector pool. The studies described here investigate the mechanistic basis of this in vivo regulation of avidity. We present data supporting in vivo avidity modulation within the early high avidity responders that results in a population of lower avidity effector cells. Changes in avidity were correlated with decreased lck expression and increased sensitivity to lck inhibitors in effector cells present at late versus early times postinfection. The possibility of tuning within select individual effectors is a previously unappreciated mechanism for the control of avidity in vivo." @default.
• W1982462300 created "2016-06-24" @default.
• W1982462300 creator A5003621059 @default.
• W1982462300 creator A5004429006 @default.
• W1982462300 creator A5064469725 @default.
• W1982462300 creator A5070041518 @default.
• W1982462300 date "2013-10-01" @default.
• W1982462300 modified "2023-09-27" @default.
• W1982462300 title "<i>In vivo</i> Modulation of Avidity in Highly Sensitive CD8⁺ Effector T Cells Following Viral Infection" @default.
• W1982462300 cites W1479760379 @default.
• W1982462300 cites W1488522044 @default.
• W1982462300 cites W1496291074 @default.
• W1982462300 cites W1501233675 @default.
• W1982462300 cites W1507930766 @default.
• W1982462300 cites W1523147669 @default.
• W1982462300 cites W1526773517 @default.
• W1982462300 cites W1541571439 @default.
• W1982462300 cites W1551744310 @default.
• W1982462300 cites W1589097025 @default.
• W1982462300 cites W1643293176 @default.
• W1982462300 cites W1828839685 @default.
• W1982462300 cites W1895045716 @default.
• W1982462300 cites W1933944805 @default.
• W1982462300 cites W1977728770 @default.
• W1982462300 cites W1978094859 @default.
• W1982462300 cites W1979769420 @default.
• W1982462300 cites W1982114584 @default.
• W1982462300 cites W1983090549 @default.
• W1982462300 cites W2012577807 @default.
• W1982462300 cites W2018702951 @default.
• W1982462300 cites W2023809975 @default.
• W1982462300 cites W2027119974 @default.
• W1982462300 cites W2027434623 @default.
• W1982462300 cites W2031482359 @default.
• W1982462300 cites W2036458764 @default.
• W1982462300 cites W2039772384 @default.
• W1982462300 cites W2041658172 @default.
• W1982462300 cites W2043518683 @default.
• W1982462300 cites W2047465993 @default.
• W1982462300 cites W2058634008 @default.
• W1982462300 cites W2060530677 @default.
• W1982462300 cites W2064621448 @default.
• W1982462300 cites W2070791475 @default.
• W1982462300 cites W2070869831 @default.
• W1982462300 cites W2077228835 @default.
• W1982462300 cites W2077825191 @default.
• W1982462300 cites W2078956671 @default.
• W1982462300 cites W2084380588 @default.
• W1982462300 cites W2090895449 @default.
• W1982462300 cites W2095705567 @default.
• W1982462300 cites W2096634178 @default.
• W1982462300 cites W2100192480 @default.
• W1982462300 cites W2102895333 @default.
• W1982462300 cites W2104157195 @default.
• W1982462300 cites W2112859782 @default.
• W1982462300 cites W2114497896 @default.
• W1982462300 cites W2116394003 @default.
• W1982462300 cites W2119869801 @default.
• W1982462300 cites W2131905612 @default.
• W1982462300 cites W2132825839 @default.
• W1982462300 cites W2135005138 @default.
• W1982462300 cites W2136555855 @default.
• W1982462300 cites W2137021531 @default.
• W1982462300 cites W2148899334 @default.
• W1982462300 cites W2158175056 @default.
• W1982462300 cites W2158514188 @default.
• W1982462300 cites W2162291240 @default.
• W1982462300 cites W2162330027 @default.
• W1982462300 cites W2162457545 @default.
• W1982462300 cites W2166093525 @default.
• W1982462300 cites W4313343519 @default.
• W1982462300 doi "https://doi.org/10.1089/vim.2013.0042" @default.
• W1982462300 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3797458" @default.
• W1982462300 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23971914" @default.
• W1982462300 hasPublicationYear "2013" @default.
• W1982462300 type Work @default.
• W1982462300 sameAs 1982462300 @default.
• W1982462300 citedByCount "2" @default.
• W1982462300 countsByYear W19824623002014 @default.
• W1982462300 crossrefType "journal-article" @default.
• W1982462300 hasAuthorship W1982462300A5003621059 @default.
• W1982462300 hasAuthorship W1982462300A5004429006 @default.
• W1982462300 hasAuthorship W1982462300A5064469725 @default.
• W1982462300 hasAuthorship W1982462300A5070041518 @default.
• W1982462300 hasBestOaLocation W19824623002 @default.
• W1982462300 hasConcept C159654299 @default.
• W1982462300 hasConcept C167672396 @default.
• W1982462300 hasConcept C179223381 @default.
• W1982462300 hasConcept C203014093 @default.
• W1982462300 hasConcept C207001950 @default.
• W1982462300 hasConcept C2908647359 @default.
• W1982462300 hasConcept C51785407 @default.
• W1982462300 hasConcept C54355233 @default.
• W1982462300 hasConcept C71924100 @default.
• W1982462300 hasConcept C86803240 @default.
• W1982462300 hasConcept C8891405 @default.
• W1982462300 hasConcept C95444343 @default.
• W1982462300 hasConcept C99454951 @default.

• next