FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1982483359> ?p ?o ?g. }

• W1982483359 endingPage "11858" @default.
• W1982483359 startingPage "11854" @default.
• W1982483359 abstract "This report presents evidence that a reduced pyrrolo[1,2-a]benzimidazole (PBI) cleaves DNA as a result of phosphate alkylation followed by hydrolysis of the resulting phosphate triester. The base-pair specificity of the phosphate alkylation results from Hoogsteen-type hydrogen bonding of the reduced PBI in the major groove at only A.T and G.C base pairs. Alkylated phosphates were detected by 31P NMR and the cleavage products were detected by 1H NMR and HPLC. Evidence is also presented that a reduced PBI interacts with DNA in the major groove rather than in the minor groove or by intercalation." @default.
• W1982483359 created "2016-06-24" @default.
• W1982483359 creator A5008476527 @default.
• W1982483359 creator A5008517719 @default.
• W1982483359 creator A5035272925 @default.
• W1982483359 date "1995-12-05" @default.
• W1982483359 modified "2023-10-16" @default.
• W1982483359 title "Evidence for DNA phosphate backbone alkylation and cleavage by pyrrolo[1,2-a]benzimidazoles: small molecules capable of causing base-pair-specific phosphodiester bond hydrolysis." @default.
• W1982483359 cites W1558516755 @default.
• W1982483359 cites W1964386510 @default.
• W1982483359 cites W1968641146 @default.
• W1982483359 cites W1985451686 @default.
• W1982483359 cites W1989992923 @default.
• W1982483359 cites W2004607245 @default.
• W1982483359 cites W2012594887 @default.
• W1982483359 cites W2015687520 @default.
• W1982483359 cites W2022870706 @default.
• W1982483359 cites W2041818114 @default.
• W1982483359 cites W2045489285 @default.
• W1982483359 cites W2046363941 @default.
• W1982483359 cites W2050598518 @default.
• W1982483359 cites W2082205587 @default.
• W1982483359 cites W2132304035 @default.
• W1982483359 cites W2950291566 @default.
• W1982483359 cites W4245950164 @default.
• W1982483359 doi "https://doi.org/10.1073/pnas.92.25.11854" @default.
• W1982483359 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/40501" @default.
• W1982483359 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8524862" @default.
• W1982483359 hasPublicationYear "1995" @default.
• W1982483359 type Work @default.
• W1982483359 sameAs 1982483359 @default.
• W1982483359 citedByCount "22" @default.
• W1982483359 countsByYear W19824833592013 @default.
• W1982483359 countsByYear W19824833592016 @default.
• W1982483359 countsByYear W19824833592019 @default.
• W1982483359 countsByYear W19824833592021 @default.
• W1982483359 countsByYear W19824833592023 @default.
• W1982483359 crossrefType "journal-article" @default.
• W1982483359 hasAuthorship W1982483359A5008476527 @default.
• W1982483359 hasAuthorship W1982483359A5008517719 @default.
• W1982483359 hasAuthorship W1982483359A5035272925 @default.
• W1982483359 hasBestOaLocation W19824833591 @default.
• W1982483359 hasConcept C104317684 @default.
• W1982483359 hasConcept C112887158 @default.
• W1982483359 hasConcept C137824038 @default.
• W1982483359 hasConcept C151730666 @default.
• W1982483359 hasConcept C161790260 @default.
• W1982483359 hasConcept C164361826 @default.
• W1982483359 hasConcept C175156509 @default.
• W1982483359 hasConcept C178790620 @default.
• W1982483359 hasConcept C185581394 @default.
• W1982483359 hasConcept C185592680 @default.
• W1982483359 hasConcept C2777132085 @default.
• W1982483359 hasConcept C2778484023 @default.
• W1982483359 hasConcept C32909587 @default.
• W1982483359 hasConcept C38441620 @default.
• W1982483359 hasConcept C43369102 @default.
• W1982483359 hasConcept C512185932 @default.
• W1982483359 hasConcept C552990157 @default.
• W1982483359 hasConcept C55493867 @default.
• W1982483359 hasConcept C67705224 @default.
• W1982483359 hasConcept C71240020 @default.
• W1982483359 hasConcept C86803240 @default.
• W1982483359 hasConcept C94412978 @default.
• W1982483359 hasConceptScore W1982483359C104317684 @default.
• W1982483359 hasConceptScore W1982483359C112887158 @default.
• W1982483359 hasConceptScore W1982483359C137824038 @default.
• W1982483359 hasConceptScore W1982483359C151730666 @default.
• W1982483359 hasConceptScore W1982483359C161790260 @default.
• W1982483359 hasConceptScore W1982483359C164361826 @default.
• W1982483359 hasConceptScore W1982483359C175156509 @default.
• W1982483359 hasConceptScore W1982483359C178790620 @default.
• W1982483359 hasConceptScore W1982483359C185581394 @default.
• W1982483359 hasConceptScore W1982483359C185592680 @default.
• W1982483359 hasConceptScore W1982483359C2777132085 @default.
• W1982483359 hasConceptScore W1982483359C2778484023 @default.
• W1982483359 hasConceptScore W1982483359C32909587 @default.
• W1982483359 hasConceptScore W1982483359C38441620 @default.
• W1982483359 hasConceptScore W1982483359C43369102 @default.
• W1982483359 hasConceptScore W1982483359C512185932 @default.
• W1982483359 hasConceptScore W1982483359C552990157 @default.
• W1982483359 hasConceptScore W1982483359C55493867 @default.
• W1982483359 hasConceptScore W1982483359C67705224 @default.
• W1982483359 hasConceptScore W1982483359C71240020 @default.
• W1982483359 hasConceptScore W1982483359C86803240 @default.
• W1982483359 hasConceptScore W1982483359C94412978 @default.
• W1982483359 hasIssue "25" @default.
• W1982483359 hasLocation W19824833591 @default.
• W1982483359 hasLocation W19824833592 @default.
• W1982483359 hasLocation W19824833593 @default.
• W1982483359 hasLocation W19824833594 @default.
• W1982483359 hasOpenAccess W1982483359 @default.
• W1982483359 hasPrimaryLocation W19824833591 @default.
• W1982483359 hasRelatedWork W1982483359 @default.
• W1982483359 hasRelatedWork W1992827354 @default.
• W1982483359 hasRelatedWork W19949609 @default.
• W1982483359 hasRelatedWork W2052417697 @default.
• W1982483359 hasRelatedWork W2066356605 @default.

• next