Matches in SemOpenAlex for { <https://semopenalex.org/work/W1982483916> ?p ?o ?g. }
- W1982483916 endingPage "298" @default.
- W1982483916 startingPage "293" @default.
- W1982483916 abstract "Human psoriasin (S100A7) has been described as a member of the family of S100 calcium-binding proteins and is over-expressed in patients suffering from psoriasis. The bovine homolog was first identified as a cow-derived respiratory allergen. Human psoriasin as well as its bovine homolog exhibit antibacterial activity especially against Escherichia coli. During E. coli mastitis, the host defence status is a cardinal factor influencing systemic disease severity, and E. coli mastitis is a common problem in dairy cattle. We therefore examined by immunoblotting and immunohistochemistry whether and in which location the bovine protein is expressed in the mammary gland and whether this expression is inducible by E. coli infection. Additionally, milk samples from the cows were investigated. To obtain an antiserum, rabbits were immunised with recombinant bovine psoriasin. Six German Holstein cows in their first lactation were used; four of them were intramammarily infected with an E. coli strain isolated from udder secretions of cows with clinical mastitis, two cows served as healthy control animals. After 24 h, cows were slaughtered and samples were collected from three different locations of the quarters. Psoriasin expression was limited to the teat cistern of the E. coli-infected cows, but was absent in the teat cistern of the non-infected cows and in the parenchyma of both groups, whereas the expression on udder skin was demonstrated in both infected and non-infected cows. Psoriasin thus appears to be a part of the local host defence mechanisms in the udder and seems to be inducible by infection with E. coli." @default.
- W1982483916 created "2016-06-24" @default.
- W1982483916 creator A5019987533 @default.
- W1982483916 creator A5030106771 @default.
- W1982483916 creator A5048343786 @default.
- W1982483916 creator A5053918022 @default.
- W1982483916 date "2010-07-01" @default.
- W1982483916 modified "2023-10-16" @default.
- W1982483916 title "The antibacterial psoriasin is induced by E. coli infection in the bovine udder" @default.
- W1982483916 cites W1963588374 @default.
- W1982483916 cites W1965517927 @default.
- W1982483916 cites W1965612425 @default.
- W1982483916 cites W1975417398 @default.
- W1982483916 cites W1980593537 @default.
- W1982483916 cites W1987287925 @default.
- W1982483916 cites W1994853124 @default.
- W1982483916 cites W2015253604 @default.
- W1982483916 cites W2016438136 @default.
- W1982483916 cites W2031400337 @default.
- W1982483916 cites W2054602599 @default.
- W1982483916 cites W2058331045 @default.
- W1982483916 cites W2065683366 @default.
- W1982483916 cites W2092663747 @default.
- W1982483916 cites W2099573376 @default.
- W1982483916 cites W2107195564 @default.
- W1982483916 cites W2107321102 @default.
- W1982483916 cites W2122054271 @default.
- W1982483916 cites W2133865157 @default.
- W1982483916 cites W2141068751 @default.
- W1982483916 cites W2149653812 @default.
- W1982483916 cites W2168739694 @default.
- W1982483916 doi "https://doi.org/10.1016/j.vetmic.2009.11.035" @default.
- W1982483916 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20074874" @default.
- W1982483916 hasPublicationYear "2010" @default.
- W1982483916 type Work @default.
- W1982483916 sameAs 1982483916 @default.
- W1982483916 citedByCount "28" @default.
- W1982483916 countsByYear W19824839162012 @default.
- W1982483916 countsByYear W19824839162013 @default.
- W1982483916 countsByYear W19824839162014 @default.
- W1982483916 countsByYear W19824839162015 @default.
- W1982483916 countsByYear W19824839162016 @default.
- W1982483916 countsByYear W19824839162017 @default.
- W1982483916 countsByYear W19824839162019 @default.
- W1982483916 countsByYear W19824839162021 @default.
- W1982483916 countsByYear W19824839162022 @default.
- W1982483916 countsByYear W19824839162023 @default.
- W1982483916 crossrefType "journal-article" @default.
- W1982483916 hasAuthorship W1982483916A5019987533 @default.
- W1982483916 hasAuthorship W1982483916A5030106771 @default.
- W1982483916 hasAuthorship W1982483916A5048343786 @default.
- W1982483916 hasAuthorship W1982483916A5053918022 @default.
- W1982483916 hasBestOaLocation W19824839162 @default.
- W1982483916 hasConcept C104317684 @default.
- W1982483916 hasConcept C121608353 @default.
- W1982483916 hasConcept C159654299 @default.
- W1982483916 hasConcept C203014093 @default.
- W1982483916 hasConcept C2776344049 @default.
- W1982483916 hasConcept C2776659692 @default.
- W1982483916 hasConcept C2776921810 @default.
- W1982483916 hasConcept C2778001805 @default.
- W1982483916 hasConcept C2779234561 @default.
- W1982483916 hasConcept C40767141 @default.
- W1982483916 hasConcept C530470458 @default.
- W1982483916 hasConcept C54355233 @default.
- W1982483916 hasConcept C547475151 @default.
- W1982483916 hasConcept C55493867 @default.
- W1982483916 hasConcept C86803240 @default.
- W1982483916 hasConcept C89423630 @default.
- W1982483916 hasConcept C91523082 @default.
- W1982483916 hasConceptScore W1982483916C104317684 @default.
- W1982483916 hasConceptScore W1982483916C121608353 @default.
- W1982483916 hasConceptScore W1982483916C159654299 @default.
- W1982483916 hasConceptScore W1982483916C203014093 @default.
- W1982483916 hasConceptScore W1982483916C2776344049 @default.
- W1982483916 hasConceptScore W1982483916C2776659692 @default.
- W1982483916 hasConceptScore W1982483916C2776921810 @default.
- W1982483916 hasConceptScore W1982483916C2778001805 @default.
- W1982483916 hasConceptScore W1982483916C2779234561 @default.
- W1982483916 hasConceptScore W1982483916C40767141 @default.
- W1982483916 hasConceptScore W1982483916C530470458 @default.
- W1982483916 hasConceptScore W1982483916C54355233 @default.
- W1982483916 hasConceptScore W1982483916C547475151 @default.
- W1982483916 hasConceptScore W1982483916C55493867 @default.
- W1982483916 hasConceptScore W1982483916C86803240 @default.
- W1982483916 hasConceptScore W1982483916C89423630 @default.
- W1982483916 hasConceptScore W1982483916C91523082 @default.
- W1982483916 hasIssue "2-4" @default.
- W1982483916 hasLocation W19824839161 @default.
- W1982483916 hasLocation W19824839162 @default.
- W1982483916 hasLocation W19824839163 @default.
- W1982483916 hasLocation W19824839164 @default.
- W1982483916 hasOpenAccess W1982483916 @default.
- W1982483916 hasPrimaryLocation W19824839161 @default.
- W1982483916 hasRelatedWork W2006137163 @default.
- W1982483916 hasRelatedWork W2101483221 @default.
- W1982483916 hasRelatedWork W2165323362 @default.
- W1982483916 hasRelatedWork W2182536686 @default.