FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1982487580> ?p ?o ?g. }

• W1982487580 endingPage "1016" @default.
• W1982487580 startingPage "1007" @default.
• W1982487580 abstract "The potential prognostic value of stem cell markers is variably reported, such as CD133 and epithelial cell adhesion molecule. However, their clinical value and significance in hepatocellular carcinoma (HCC) remain controversial. The aim of this study was to carry out a meta-analysis of literature evaluating CD133 and epithelial cell adhesion molecule expression as prognostic factors in HCC and to determine the association between cancer stem cells (CSCs) and common clinical and pathologic features of HCC. The relevant literature was identified using Science Direct, EMBASE, and PubMed. Outcome measures included disease-free survival, overall survival, and relevant pathological parameters. Meta-analyses were carried out using Review Manager, version 5.2. Twelve eligible articles involving 1344 patients were included. Meta-analyses showed that the presence of CSCs was significantly associated with a poor histological grade (OR=3.16, P=0.003) and elevated serum α-fetoprotein level (OR=2.68, P<0.00001). However, there were no significant relations between the presence of CSCs and tumor size, tumor stage, hepatitis, or cirrhosis. The presence of CSCs was significantly associated with poor survival, including overall survival (HR=1.62, P<0.00001) and disease-free survival (HR=1.85, P<0.00001). On the basis of current retrospective evidence, the presence of CSCs is associated with poor histopathologic grade and worse survival in patients with HCC and CD133 plays a significant role in predicting the clinical outcome. Further extensive experimental and clinical research should be carried out to evaluate the role of these markers in clinical practice." @default.
• W1982487580 created "2016-06-24" @default.
• W1982487580 creator A5040726730 @default.
• W1982487580 creator A5043890633 @default.
• W1982487580 creator A5080239482 @default.
• W1982487580 date "2013-09-01" @default.
• W1982487580 modified "2023-09-24" @default.
• W1982487580 title "Relevant markers of cancer stem cells indicate a poor prognosis in hepatocellular carcinoma patients" @default.
• W1982487580 cites W1984863619 @default.
• W1982487580 cites W1986815130 @default.
• W1982487580 cites W1990767426 @default.
• W1982487580 cites W1999356404 @default.
• W1982487580 cites W2005397767 @default.
• W1982487580 cites W2007500450 @default.
• W1982487580 cites W2009886857 @default.
• W1982487580 cites W2021135937 @default.
• W1982487580 cites W2029634531 @default.
• W1982487580 cites W2059346885 @default.
• W1982487580 cites W2066824210 @default.
• W1982487580 cites W2088095316 @default.
• W1982487580 cites W2088629624 @default.
• W1982487580 cites W2095789123 @default.
• W1982487580 cites W2100117577 @default.
• W1982487580 cites W2106513086 @default.
• W1982487580 cites W2106787323 @default.
• W1982487580 cites W2125435699 @default.
• W1982487580 cites W2126133903 @default.
• W1982487580 cites W2158741313 @default.
• W1982487580 cites W2168106507 @default.
• W1982487580 doi "https://doi.org/10.1097/meg.0b013e32836019d8" @default.
• W1982487580 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23478672" @default.
• W1982487580 hasPublicationYear "2013" @default.
• W1982487580 type Work @default.
• W1982487580 sameAs 1982487580 @default.
• W1982487580 citedByCount "49" @default.
• W1982487580 countsByYear W19824875802013 @default.
• W1982487580 countsByYear W19824875802014 @default.
• W1982487580 countsByYear W19824875802015 @default.
• W1982487580 countsByYear W19824875802016 @default.
• W1982487580 countsByYear W19824875802017 @default.
• W1982487580 countsByYear W19824875802018 @default.
• W1982487580 countsByYear W19824875802019 @default.
• W1982487580 countsByYear W19824875802020 @default.
• W1982487580 countsByYear W19824875802021 @default.
• W1982487580 countsByYear W19824875802022 @default.
• W1982487580 countsByYear W19824875802023 @default.
• W1982487580 crossrefType "journal-article" @default.
• W1982487580 hasAuthorship W1982487580A5040726730 @default.
• W1982487580 hasAuthorship W1982487580A5043890633 @default.
• W1982487580 hasAuthorship W1982487580A5080239482 @default.
• W1982487580 hasConcept C121608353 @default.
• W1982487580 hasConcept C126322002 @default.
• W1982487580 hasConcept C142724271 @default.
• W1982487580 hasConcept C143998085 @default.
• W1982487580 hasConcept C146357865 @default.
• W1982487580 hasConcept C151730666 @default.
• W1982487580 hasConcept C207886595 @default.
• W1982487580 hasConcept C2776231280 @default.
• W1982487580 hasConcept C2776677690 @default.
• W1982487580 hasConcept C2777214474 @default.
• W1982487580 hasConcept C2777546739 @default.
• W1982487580 hasConcept C2778019345 @default.
• W1982487580 hasConcept C28328180 @default.
• W1982487580 hasConcept C54355233 @default.
• W1982487580 hasConcept C55427017 @default.
• W1982487580 hasConcept C71924100 @default.
• W1982487580 hasConcept C86803240 @default.
• W1982487580 hasConcept C90924648 @default.
• W1982487580 hasConceptScore W1982487580C121608353 @default.
• W1982487580 hasConceptScore W1982487580C126322002 @default.
• W1982487580 hasConceptScore W1982487580C142724271 @default.
• W1982487580 hasConceptScore W1982487580C143998085 @default.
• W1982487580 hasConceptScore W1982487580C146357865 @default.
• W1982487580 hasConceptScore W1982487580C151730666 @default.
• W1982487580 hasConceptScore W1982487580C207886595 @default.
• W1982487580 hasConceptScore W1982487580C2776231280 @default.
• W1982487580 hasConceptScore W1982487580C2776677690 @default.
• W1982487580 hasConceptScore W1982487580C2777214474 @default.
• W1982487580 hasConceptScore W1982487580C2777546739 @default.
• W1982487580 hasConceptScore W1982487580C2778019345 @default.
• W1982487580 hasConceptScore W1982487580C28328180 @default.
• W1982487580 hasConceptScore W1982487580C54355233 @default.
• W1982487580 hasConceptScore W1982487580C55427017 @default.
• W1982487580 hasConceptScore W1982487580C71924100 @default.
• W1982487580 hasConceptScore W1982487580C86803240 @default.
• W1982487580 hasConceptScore W1982487580C90924648 @default.
• W1982487580 hasIssue "9" @default.
• W1982487580 hasLocation W19824875801 @default.
• W1982487580 hasLocation W19824875802 @default.
• W1982487580 hasOpenAccess W1982487580 @default.
• W1982487580 hasPrimaryLocation W19824875801 @default.
• W1982487580 hasRelatedWork W1995827984 @default.
• W1982487580 hasRelatedWork W2266860383 @default.
• W1982487580 hasRelatedWork W2766588635 @default.
• W1982487580 hasRelatedWork W2958587449 @default.
• W1982487580 hasRelatedWork W3030449887 @default.
• W1982487580 hasRelatedWork W3032094436 @default.
• W1982487580 hasRelatedWork W3048238215 @default.

• next