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- W1982502802 abstract "The objective is to study the tissue reaction of the paralyzed vocal cord in response to the injection of particulate plastics in a rabbit model. Forty-five New Zealand rabbits with surgical vocal-fold paralysis were used in the study. Histologic reactions of the larynx and the regional lymph nodes were analyzed by a single blinded pathologist at 6 weeks and 6 months after a vocal-cord injection of Teflon or of silicone elastomer. Macroscopic studies of the liver, lungs, spleen, kidney, and brain were performed. The histological study showed a greater proportion of chronic granulomatous inflammation in animals injected with silicone than in those injected with Teflon. The immunohistochemical study showed a higher degree of phagocytosis of Teflon particles than of the silicone particles. The silicone group presented a more severe fibrous reaction than the Teflon group, but the difference was not significant. No migration particles were found. It is concluded that silicone, having a greater viscosity than Teflon because of the size of its particles, induces more fibrosis and a larger proportion of foreign giant cells in the host. Due to this histological reaction, silicone particles present greater anchorage and stability." @default.
- W1982502802 created "2016-06-24" @default.
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- W1982502802 date "2003-09-12" @default.
- W1982502802 modified "2023-10-16" @default.
- W1982502802 title "Polydimethylsiloxane versus polytetrafluoroethylene for vocal fold medialization: Histologic evaluation in a rabbit model" @default.
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- W1982502802 doi "https://doi.org/10.1002/jbm.b.10061" @default.
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