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- W1982503178 abstract "Many amidine-based molecules are known to be antagonists of the fibrinogen−GP IIb-IIIa interaction, therefore useful in the treatment of thrombotic deseases. Here we report the solid-phase synthesis of a small library of amidines, starting from high-loading dendrimerised TentaGel beads, using resin-bound 4-amidinobenzoic acid as a template. These compounds mimic the structure of known active compounds like Lamifiban (Ro44-9883) and TAK-029; the first solid-phase synthesis of which is also reported in this paper." @default.
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- W1982503178 date "2000-12-01" @default.
- W1982503178 modified "2023-10-14" @default.
- W1982503178 title "Solid-Phase Synthesis of Amidine-Based GP IIb-IIIa Antagonists on Dendrimer Resin Beads" @default.
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- W1982503178 doi "https://doi.org/10.1002/1099-0690(200012)2000:23<3887::aid-ejoc3887>3.0.co;2-t" @default.
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