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• W1982545437 abstract "Background Our institution experienced an increase in the frequency of vancomycin-resistant enterococci (VRE) clinical isolates, which rose 5-fold from 2004 to 2005. We sought to measure the prevalence of VRE carriage among medical inpatients in a tertiary hospital in Jerusalem and estimate the rate of acquisition during hospitalization. Methods During 2006, we performed 3 cross-sectional surveys, including 1039 patients, representing 3 phases of hospitalization: admission, hospital stay, and discharge. Perianal/stool samples were cultured for VRE. Results VRE carriage was 3.8% (95% confidence interval [CI] = 1.8% to 6.9%) on admission, 15% (95% CI = 9% to 23%) at discharge, and 32% (95% CI = 24% to 40%) among inpatients. Among inpatient carriers, 60% of the isolates represented a single strain. Recent previous hospitalization was the most significant predictor for identifying carriers on admission. Conclusions Our study demonstrates that substantial VRE transmission occurred during hospitalization. Identification of carriers on admission should supplement effective application of infection control methods in attempting to decrease VRE nosocomial spread and burden. Our institution experienced an increase in the frequency of vancomycin-resistant enterococci (VRE) clinical isolates, which rose 5-fold from 2004 to 2005. We sought to measure the prevalence of VRE carriage among medical inpatients in a tertiary hospital in Jerusalem and estimate the rate of acquisition during hospitalization. During 2006, we performed 3 cross-sectional surveys, including 1039 patients, representing 3 phases of hospitalization: admission, hospital stay, and discharge. Perianal/stool samples were cultured for VRE. VRE carriage was 3.8% (95% confidence interval [CI] = 1.8% to 6.9%) on admission, 15% (95% CI = 9% to 23%) at discharge, and 32% (95% CI = 24% to 40%) among inpatients. Among inpatient carriers, 60% of the isolates represented a single strain. Recent previous hospitalization was the most significant predictor for identifying carriers on admission. Our study demonstrates that substantial VRE transmission occurred during hospitalization. Identification of carriers on admission should supplement effective application of infection control methods in attempting to decrease VRE nosocomial spread and burden." @default.
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• W1982545437 date "2009-03-01" @default.
• W1982545437 modified "2023-10-14" @default.
• W1982545437 title "Acquisition of vancomycin-resistant enterococci in internal medicine wards" @default.
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• W1982545437 doi "https://doi.org/10.1016/j.ajic.2008.04.260" @default.
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