FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1982566038> ?p ?o ?g. }

• W1982566038 endingPage "2696.e5" @default.
• W1982566038 startingPage "2696.e1" @default.
• W1982566038 abstract "Despite the recent identification of several novel risk genes for Alzheimer's disease (AD), little is known about their influence on the age at onset (AAO) of AD. The AAO is a phenotype with a heritable component distinct from disease risk and may be a useful trait to study in the context of developing interventions for delaying the onset of AD. We studied the influence of 10 recently identified AD risk genes and APOE in relation to AAO in a large cohort of AD patients (N = 2569). We find that the novel AD risk gene, PICALM, exerts a small effect on the AAO of AD with earlier disease onset in risk allele carriers. In addition, we confirmed the previously reported association between the APOE ε4 allele and earlier disease onset. None of the other AD risk genes influenced AAO of AD. Our results suggest that besides APOE, other genes associated with AD risk do not exert large effects on the AAO phenotype of AD." @default.
• W1982566038 created "2016-06-24" @default.
• W1982566038 creator A5069442898 @default.
• W1982566038 creator A5079276216 @default.
• W1982566038 creator A5089482025 @default.
• W1982566038 date "2013-11-01" @default.
• W1982566038 modified "2023-10-16" @default.
• W1982566038 title "Alzheimer's disease risk genes and the age-at-onset phenotype" @default.
• W1982566038 cites W1554557480 @default.
• W1982566038 cites W1965616054 @default.
• W1982566038 cites W1966378425 @default.
• W1982566038 cites W1966831629 @default.
• W1982566038 cites W1988427943 @default.
• W1982566038 cites W1989178832 @default.
• W1982566038 cites W2001199794 @default.
• W1982566038 cites W2002989619 @default.
• W1982566038 cites W2009129230 @default.
• W1982566038 cites W2011503072 @default.
• W1982566038 cites W2012733162 @default.
• W1982566038 cites W2023399477 @default.
• W1982566038 cites W2026973341 @default.
• W1982566038 cites W2036405583 @default.
• W1982566038 cites W2040423788 @default.
• W1982566038 cites W2046234674 @default.
• W1982566038 cites W2057162011 @default.
• W1982566038 cites W2068352626 @default.
• W1982566038 cites W2073483498 @default.
• W1982566038 cites W2079787624 @default.
• W1982566038 cites W2079873327 @default.
• W1982566038 cites W2087278953 @default.
• W1982566038 cites W2121820194 @default.
• W1982566038 cites W2124341714 @default.
• W1982566038 cites W2125993125 @default.
• W1982566038 cites W2129494556 @default.
• W1982566038 cites W2133691274 @default.
• W1982566038 cites W2134448489 @default.
• W1982566038 cites W2138357019 @default.
• W1982566038 cites W2145210308 @default.
• W1982566038 cites W2152119060 @default.
• W1982566038 cites W2154861477 @default.
• W1982566038 cites W2162988145 @default.
• W1982566038 cites W2169103586 @default.
• W1982566038 cites W2171610997 @default.
• W1982566038 cites W2172263413 @default.
• W1982566038 cites W3214092816 @default.
• W1982566038 cites W4245491202 @default.
• W1982566038 doi "https://doi.org/10.1016/j.neurobiolaging.2013.05.028" @default.
• W1982566038 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4038407" @default.
• W1982566038 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23870418" @default.
• W1982566038 hasPublicationYear "2013" @default.
• W1982566038 type Work @default.
• W1982566038 sameAs 1982566038 @default.
• W1982566038 citedByCount "25" @default.
• W1982566038 countsByYear W19825660382014 @default.
• W1982566038 countsByYear W19825660382015 @default.
• W1982566038 countsByYear W19825660382016 @default.
• W1982566038 countsByYear W19825660382017 @default.
• W1982566038 countsByYear W19825660382018 @default.
• W1982566038 countsByYear W19825660382020 @default.
• W1982566038 countsByYear W19825660382021 @default.
• W1982566038 countsByYear W19825660382022 @default.
• W1982566038 countsByYear W19825660382023 @default.
• W1982566038 crossrefType "journal-article" @default.
• W1982566038 hasAuthorship W1982566038A5069442898 @default.
• W1982566038 hasAuthorship W1982566038A5079276216 @default.
• W1982566038 hasAuthorship W1982566038A5089482025 @default.
• W1982566038 hasBestOaLocation W19825660382 @default.
• W1982566038 hasConcept C104317684 @default.
• W1982566038 hasConcept C106208931 @default.
• W1982566038 hasConcept C126322002 @default.
• W1982566038 hasConcept C127716648 @default.
• W1982566038 hasConcept C135763542 @default.
• W1982566038 hasConcept C151730666 @default.
• W1982566038 hasConcept C153209595 @default.
• W1982566038 hasConcept C180754005 @default.
• W1982566038 hasConcept C2777767895 @default.
• W1982566038 hasConcept C2779134260 @default.
• W1982566038 hasConcept C2779343474 @default.
• W1982566038 hasConcept C502032728 @default.
• W1982566038 hasConcept C54355233 @default.
• W1982566038 hasConcept C57089818 @default.
• W1982566038 hasConcept C60644358 @default.
• W1982566038 hasConcept C71924100 @default.
• W1982566038 hasConcept C86803240 @default.
• W1982566038 hasConceptScore W1982566038C104317684 @default.
• W1982566038 hasConceptScore W1982566038C106208931 @default.
• W1982566038 hasConceptScore W1982566038C126322002 @default.
• W1982566038 hasConceptScore W1982566038C127716648 @default.
• W1982566038 hasConceptScore W1982566038C135763542 @default.
• W1982566038 hasConceptScore W1982566038C151730666 @default.
• W1982566038 hasConceptScore W1982566038C153209595 @default.
• W1982566038 hasConceptScore W1982566038C180754005 @default.
• W1982566038 hasConceptScore W1982566038C2777767895 @default.
• W1982566038 hasConceptScore W1982566038C2779134260 @default.
• W1982566038 hasConceptScore W1982566038C2779343474 @default.
• W1982566038 hasConceptScore W1982566038C502032728 @default.
• W1982566038 hasConceptScore W1982566038C54355233 @default.
• W1982566038 hasConceptScore W1982566038C57089818 @default.

• next