FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1982650949> ?p ?o ?g. }

• W1982650949 abstract "Compliance with estrogen replacement therapy (ERT) following surgical menopause is poor. In women who have a family history of ovarian cancer, fear of the oncogenic potential of estrogen might affect compliance with ERT following oophorectomy. Compliance with ERT in such a select group of women has not been previously reported. The aim of the present study was to report on compliance with and side effects of ERT in women with a family history of ovarian cancer who underwent oophorectomy either prophylactically or for benign disease. Eighty women with a family history of ovarian cancer who underwent oophorectomy at Roswell Park Cancer Institute were followed for a median duration of 4.2 years (range, 5 months to 14 years). Of the 76 women who were given prescriptions for ERT, the rates of commencement and maintenance of ERT at 1, 2, and 5 years were calculated. Side effects related to the different modalities of ERT were recorded. Seventy-one of 76 women (93.4%) who were given prescriptions for ERT initiated treatment. The rate of commencement of ERT was higher in premenopausal than in postmenopausal women (98.3% versus 75%, respectively, P = 0.003). Except for one patient who developed breast cancer after the oophorectomy and was advised to stop estrogen, all patients said they continued to use ERT. The maintenance rates at 1, 2, and 5 years were 100% as per patients' history. The pharmacy records for ERT prescription refills were reviewed for 52 patients who were on ERT for more than 1 year. ERT compliance was confirmed in 42 patients (80.7%). Seven of 30 patients (23.3%) who retained their uterus developed irregular uterine bleeding and 4 underwent endometrial biopsies. The incidence of irregular uterine bleeding was significantly higher after continuous compared to cyclic estrogen and progestogen (37.6 and 7% respectively, P = 0.049). Four patients (5.6%) complained of hot flashes and were managed by changing the dose or formula of estrogen. Compliance with ERT among patients with a family history of ovarian cancer who underwent oophorectomy either prophylactically or for benign disease was excellent. The presence of the uterus and the incidence of irregular uterine bleeding did not affect patients' compliance with ERT." @default.
• W1982650949 created "2016-06-24" @default.
• W1982650949 creator A5007139283 @default.
• W1982650949 creator A5023856630 @default.
• W1982650949 creator A5033195210 @default.
• W1982650949 creator A5040490022 @default.
• W1982650949 creator A5068154792 @default.
• W1982650949 date "1997-07-01" @default.
• W1982650949 modified "2023-09-27" @default.
• W1982650949 title "Estrogen Replacement Therapy Following Oophorectomy in Women with a Family History of Ovarian Cancer" @default.
• W1982650949 cites W1546797522 @default.
• W1982650949 cites W1849654724 @default.
• W1982650949 cites W1894508692 @default.
• W1982650949 cites W1963886401 @default.
• W1982650949 cites W1964321896 @default.
• W1982650949 cites W2005690480 @default.
• W1982650949 cites W2007841512 @default.
• W1982650949 cites W2010657017 @default.
• W1982650949 cites W2011426006 @default.
• W1982650949 cites W2013449928 @default.
• W1982650949 cites W2039860789 @default.
• W1982650949 cites W2051028982 @default.
• W1982650949 cites W2052858021 @default.
• W1982650949 cites W2054669823 @default.
• W1982650949 cites W2088353841 @default.
• W1982650949 cites W2414779359 @default.
• W1982650949 cites W2415945971 @default.
• W1982650949 cites W35530342 @default.
• W1982650949 doi "https://doi.org/10.1006/gyno.1997.4723" @default.
• W1982650949 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9234929" @default.
• W1982650949 hasPublicationYear "1997" @default.
• W1982650949 type Work @default.
• W1982650949 sameAs 1982650949 @default.
• W1982650949 citedByCount "11" @default.
• W1982650949 crossrefType "journal-article" @default.
• W1982650949 hasAuthorship W1982650949A5007139283 @default.
• W1982650949 hasAuthorship W1982650949A5023856630 @default.
• W1982650949 hasAuthorship W1982650949A5033195210 @default.
• W1982650949 hasAuthorship W1982650949A5040490022 @default.
• W1982650949 hasAuthorship W1982650949A5068154792 @default.
• W1982650949 hasConcept C121608353 @default.
• W1982650949 hasConcept C126322002 @default.
• W1982650949 hasConcept C131872663 @default.
• W1982650949 hasConcept C141071460 @default.
• W1982650949 hasConcept C2777164284 @default.
• W1982650949 hasConcept C2777696064 @default.
• W1982650949 hasConcept C2778562196 @default.
• W1982650949 hasConcept C2779279991 @default.
• W1982650949 hasConcept C2779494336 @default.
• W1982650949 hasConcept C2780159708 @default.
• W1982650949 hasConcept C2780427987 @default.
• W1982650949 hasConcept C2781179581 @default.
• W1982650949 hasConcept C29456083 @default.
• W1982650949 hasConcept C530470458 @default.
• W1982650949 hasConcept C71924100 @default.
• W1982650949 hasConceptScore W1982650949C121608353 @default.
• W1982650949 hasConceptScore W1982650949C126322002 @default.
• W1982650949 hasConceptScore W1982650949C131872663 @default.
• W1982650949 hasConceptScore W1982650949C141071460 @default.
• W1982650949 hasConceptScore W1982650949C2777164284 @default.
• W1982650949 hasConceptScore W1982650949C2777696064 @default.
• W1982650949 hasConceptScore W1982650949C2778562196 @default.
• W1982650949 hasConceptScore W1982650949C2779279991 @default.
• W1982650949 hasConceptScore W1982650949C2779494336 @default.
• W1982650949 hasConceptScore W1982650949C2780159708 @default.
• W1982650949 hasConceptScore W1982650949C2780427987 @default.
• W1982650949 hasConceptScore W1982650949C2781179581 @default.
• W1982650949 hasConceptScore W1982650949C29456083 @default.
• W1982650949 hasConceptScore W1982650949C530470458 @default.
• W1982650949 hasConceptScore W1982650949C71924100 @default.
• W1982650949 hasLocation W19826509491 @default.
• W1982650949 hasLocation W19826509492 @default.
• W1982650949 hasOpenAccess W1982650949 @default.
• W1982650949 hasPrimaryLocation W19826509491 @default.
• W1982650949 hasRelatedWork W1937161249 @default.
• W1982650949 hasRelatedWork W1986585253 @default.
• W1982650949 hasRelatedWork W1989359868 @default.
• W1982650949 hasRelatedWork W2027668441 @default.
• W1982650949 hasRelatedWork W2035976513 @default.
• W1982650949 hasRelatedWork W2112715835 @default.
• W1982650949 hasRelatedWork W2124822676 @default.
• W1982650949 hasRelatedWork W2137015189 @default.
• W1982650949 hasRelatedWork W2277921451 @default.
• W1982650949 hasRelatedWork W2403503433 @default.
• W1982650949 isParatext "false" @default.
• W1982650949 isRetracted "false" @default.
• W1982650949 magId "1982650949" @default.
• W1982650949 workType "article" @default.