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• W1982681261 abstract "The immune system represents our primary defense system against foreign intrusion, including pathogens as well as particles. In order to understand the potential toxicity of engineered nanomaterials of ever increasing sophistication, it is necessary to understand the sophistication of the immune system with its multiple, specialized cell types and soluble mediators. Moreover, it is important to consider not only material-intrinsic properties of the pristine nanomaterial, but also the acquired, context-dependent 'identity' of a nanomaterial in a living system resulting from the adsorption of biomolecules on its surface. The immune system has evolved to recognize a vast array of microbes through so-called pattern recognition; we discuss in the present review whether engineered nanomaterials with or without a corona of biomolecules could also be sensed as 'pathogens' by immune-competent cells." @default.
• W1982681261 created "2016-06-24" @default.
• W1982681261 creator A5003243714 @default.
• W1982681261 creator A5038844699 @default.
• W1982681261 date "2015-09-01" @default.
• W1982681261 modified "2023-10-03" @default.
• W1982681261 title "It takes two to tango: Understanding the interactions between engineered nanomaterials and the immune system" @default.
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