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• W1982703853 abstract "Background/Obiectives: Endoscopic elastic band ligation in eradicating esophageal varices has been shown to be an effective, safe, easy-to-do procedure with few untoward effects. This clinical trial compared the mean number of treatment sessions needed to eradicate esophageal varices and the safety of the Multi-site band ligation (banding 2 sites on the same varix) to those of the Conventional band ligation (banding 1 site on the same varix). Methods: This was a prospective randomized controlled clinical trial. Cirrhotics older than 18 years of age with grade 3 or 4 esophageal varices associated with red color signs were included. The patients had gastric varices, upper gastrointestinal hemorrhage, hepatic encephalopathy, or hepatorenal syndrome, those had been administering with beta blockers or isosorbid mononitrates, those had been treated esophageal varices via endoscopy all were excluded. The patients in the Multi-site band ligation group were ligated two sites on the same varix in the range of 5 cm proximal to Z line, whereas those in the Conventional band ligation group(controlled group) were only ligated one site at the most distal end of each varix. Repeat ligation treatment sessions aimed at eradication of varices were conducted at 14- to 21- day intervals until varices in the distal esophagus were obliterated. Results: 12 patients were enrolled in the Multi-site band ligation group and 9 patients in the controlled group. There were no significant differences between the two groups with regard to age, gender, Child classification, the number and the grade of varices(p>0.05). Varices were eradicated in 11 out of 12 patients in the Multi-site band ligation group and in 7 out of 9 patients in the controlled group (p>0.05). The mean number of treatment sessions needed to eradicate esophageal varices in the Multi-site band ligation group were significantly fewer than those in the controlled group (2 versus 3.85 sessions, respectively) (p=0.01). There were no significant differences between the two groups with regard to complications and adverse effects due to the procedure (p>0.05). Conclusions: Multi-site band ligation was as effective and safe in eradicating esophageal varices as Conventional band ligation was. But, Multi-site band ligation-treated patients achieved eradication of varices with fewer sessions of treatment than those treated with Conventional band ligation." @default.
• W1982703853 created "2016-06-24" @default.
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• W1982703853 date "2009-04-01" @default.
• W1982703853 modified "2023-10-16" @default.
• W1982703853 title "Efficacy of Endoscopic Multi-Site Band Ligation in Eradicating Esophageal Varices" @default.
• W1982703853 doi "https://doi.org/10.1016/j.gie.2009.03.528" @default.
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