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- W1982711835 abstract "Abstract Die Reaktion von 1‐substituierten 2‐Alkyl‐5‐nitroimidazolen mit tert.‐Butoxymethylenbis‐(dimethylamin) ergab die 2‐(2‐Dimethylaminovinyl)imidazolderivate 8a‐g (Tabelle 1). Die Derivate 8a und f wurden zu den verschiedenartigen 2‐Dimethylaminovinylketonen 10 bzw. 11 umgesetzt. Aus diesen Schlüsselverbindungen wurden 5‐Nitroimidazole erhalten, die in 2‐Position einen Pyrazolylrest (Tabellen 2 und 4 sowie Verbindungen 16a, b, 17 und 18 ) oder einen Pyrimidinylrest (Tabelle 3) tragen. Über die antimikrobielle Wirkung dieser Verbindungen in vitro wird berichtet. Verbindung 8a diente auch zur Darstellung des 1‐Methyl‐5‐nitro‐2‐imidazolcarbaldehyds 4a , einem Zwischenprodukt der Synthese des Trichomonadenmittels 1d ." @default.
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- W1982711835 date "1975-09-24" @default.
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- W1982711835 title "Chemotherapeutische Nitroheterocyclen, XIX1) Darstellung von 5-Nitroimidazolen mit Heterocyclen in 2-Position" @default.
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- W1982711835 doi "https://doi.org/10.1002/jlac.197519750724" @default.
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