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- W1982716002 abstract "Two new recombinants of avermectin polyketide synthases were constructed by domain and module swapping in Streptomyces avermitilis 73-12. However, only the strain, S. avermitilis OI-31, formed by domain substitution could produce ivermectin. Analysis of the ivermectin synthesized gene cluster showed that decreased amount of aveC transcripts was one of the factors causing low yield of ivermectin. Overexpression of aveC could improve ivermectin yield." @default.
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- W1982716002 date "2008-10-01" @default.
- W1982716002 modified "2023-10-06" @default.
- W1982716002 title "Engineering of avermectin biosynthetic genes to improve production of ivermectin in Streptomyces avermitilis" @default.
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- W1982716002 doi "https://doi.org/10.1016/j.bmcl.2008.09.061" @default.
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