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- W1982746504 abstract "The properties of B104, a new dispersed repeated gene family of Drosophila melanogaster are described. B104 was first discovered in a screen for genes differentially expressed at early embryonic development. The typical B104 element is 8.7 × 103 base-pairs in size and flanked by direct terminal repeats 429 base-pairs (bp) long. It is present in about 80 and 95 copies per haploid genome in Oregon R embryonic DNA and in Kcl cell line DNA, respectively, and accounts for about 0.4% of the D. melanogaster genome. While most of the B104 copies are closely conserved, a variant containing a 1.0 × 103 bp deletion as well as one containing a 2.4 × 103bp insertion have been found. B104 sequences are found in one large (about 8 × 103bp) and several short (0.8 to 1.2 × 103bp) transcripts. The DNA sequence of both terminal repeats in one element and of one terminal repeat in a second element was determined. In addition, two B104 complementary DNA clones originating from transcripts initiated and terminated, respectively, in the terminal repeat were also sequenced. The sequence data indicate: (1) that the B104 element is flanked by a 5 bp direct repeat; (2) that the sequence just internal to the left repeat shares homology with the transfer RNA primer binding site of retroviruses; and (3) that the B104 terminal repeat is redundantly transcribed in a manner typical of proviruses of vertebrate retroviruses." @default.
- W1982746504 created "2016-06-24" @default.
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- W1982746504 date "1982-05-01" @default.
- W1982746504 modified "2023-10-01" @default.
- W1982746504 title "B104, a new dispersed repeated gene family in Drosophila melanogaster and its analogies with retroviruses" @default.
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- W1982746504 doi "https://doi.org/10.1016/0022-2836(82)90470-3" @default.
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