FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1982749890> ?p ?o ?g. }

• W1982749890 endingPage "239" @default.
• W1982749890 startingPage "234" @default.
• W1982749890 abstract "It has previously only been possible to assess osteoclastic bone resorption in intact bone, where other cell types may modify or mediate osteoclastic responses to environmental agents. We have recently developed techniques which enable us to measure bone resorption by osteoclasts extracted from bone and have used these techniques to assess the effects of prostaglandins (PGs) and calcium-regulating hormones on bone resorption by these cells. Osteoclasts were mechanically disaggregated from neonatal rabbit long bones and cultured on slices of devitalized cortical bone for 8 or 24 h. After this time, osteoclasts were associated with the appearance in the scanning electron microscope of characteristic resorption pits, the volume of which was calculated by computer-assisted morphometric and stereophotogrammetric techniques after removal of cells. Salmon calcitonin inhibited osteoclastic bone resorption at concentrations of 1 pg/ml and above, while PTH and 1,25-dihydroxyvitamin D3 were without significant effect. This suggests that the latter hormones do not increase bone resorption in intact bone through a direct effect on osteoclasts. PGI2, PGE1, and PGE2, all of which are known to stimulate resorption when added to intact bone, paradoxically reduced resorption in our cultures. It appears likely that PGs act as direct inhibitors of osteoclastic bone resorption but have an additional effect on other cells in bone, which are induced by PGs to cause osteoclastic stimulation." @default.
• W1982749890 created "2016-06-24" @default.
• W1982749890 creator A5006153416 @default.
• W1982749890 creator A5022543438 @default.
• W1982749890 creator A5073697395 @default.
• W1982749890 creator A5078546100 @default.
• W1982749890 date "1985-01-01" @default.
• W1982749890 modified "2023-09-23" @default.
• W1982749890 title "The Effect of Calcium-Regulating Hormones and Prostaglandins on Bone Resorption by Osteoclasts Disaggregated from Neonatal Rabbit Bones*" @default.
• W1982749890 cites W1581434205 @default.
• W1982749890 cites W1596671341 @default.
• W1982749890 cites W1964324757 @default.
• W1982749890 cites W1965045236 @default.
• W1982749890 cites W1965382934 @default.
• W1982749890 cites W1966313141 @default.
• W1982749890 cites W1966458993 @default.
• W1982749890 cites W1969429995 @default.
• W1982749890 cites W1974402772 @default.
• W1982749890 cites W1977077746 @default.
• W1982749890 cites W1979980462 @default.
• W1982749890 cites W1981119778 @default.
• W1982749890 cites W1981293067 @default.
• W1982749890 cites W1983547224 @default.
• W1982749890 cites W1999968337 @default.
• W1982749890 cites W2007753723 @default.
• W1982749890 cites W2017497435 @default.
• W1982749890 cites W2026884931 @default.
• W1982749890 cites W2028318691 @default.
• W1982749890 cites W2033922702 @default.
• W1982749890 cites W2035641016 @default.
• W1982749890 cites W2037721547 @default.
• W1982749890 cites W2040337853 @default.
• W1982749890 cites W2043355910 @default.
• W1982749890 cites W2043961269 @default.
• W1982749890 cites W2045981686 @default.
• W1982749890 cites W2056556436 @default.
• W1982749890 cites W2058707027 @default.
• W1982749890 cites W2067986741 @default.
• W1982749890 cites W2082559281 @default.
• W1982749890 cites W2093052550 @default.
• W1982749890 cites W2098129520 @default.
• W1982749890 cites W2117935381 @default.
• W1982749890 cites W2126512686 @default.
• W1982749890 cites W2131512996 @default.
• W1982749890 cites W2155510455 @default.
• W1982749890 cites W2162997702 @default.
• W1982749890 cites W2415661391 @default.
• W1982749890 cites W2417966299 @default.
• W1982749890 cites W2444469871 @default.
• W1982749890 cites W66839044 @default.
• W1982749890 doi "https://doi.org/10.1210/endo-116-1-234" @default.
• W1982749890 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3880540" @default.
• W1982749890 hasPublicationYear "1985" @default.
• W1982749890 type Work @default.
• W1982749890 sameAs 1982749890 @default.
• W1982749890 citedByCount "406" @default.
• W1982749890 countsByYear W19827498902012 @default.
• W1982749890 countsByYear W19827498902013 @default.
• W1982749890 countsByYear W19827498902015 @default.
• W1982749890 countsByYear W19827498902016 @default.
• W1982749890 countsByYear W19827498902017 @default.
• W1982749890 countsByYear W19827498902018 @default.
• W1982749890 countsByYear W19827498902019 @default.
• W1982749890 countsByYear W19827498902020 @default.
• W1982749890 countsByYear W19827498902021 @default.
• W1982749890 countsByYear W19827498902022 @default.
• W1982749890 crossrefType "journal-article" @default.
• W1982749890 hasAuthorship W1982749890A5006153416 @default.
• W1982749890 hasAuthorship W1982749890A5022543438 @default.
• W1982749890 hasAuthorship W1982749890A5073697395 @default.
• W1982749890 hasAuthorship W1982749890A5078546100 @default.
• W1982749890 hasConcept C126322002 @default.
• W1982749890 hasConcept C133605539 @default.
• W1982749890 hasConcept C134018914 @default.
• W1982749890 hasConcept C146562846 @default.
• W1982749890 hasConcept C170033053 @default.
• W1982749890 hasConcept C170493617 @default.
• W1982749890 hasConcept C185592680 @default.
• W1982749890 hasConcept C2776033226 @default.
• W1982749890 hasConcept C2779627488 @default.
• W1982749890 hasConcept C519063684 @default.
• W1982749890 hasConcept C673006 @default.
• W1982749890 hasConcept C71315377 @default.
• W1982749890 hasConcept C71924100 @default.
• W1982749890 hasConcept C86803240 @default.
• W1982749890 hasConceptScore W1982749890C126322002 @default.
• W1982749890 hasConceptScore W1982749890C133605539 @default.
• W1982749890 hasConceptScore W1982749890C134018914 @default.
• W1982749890 hasConceptScore W1982749890C146562846 @default.
• W1982749890 hasConceptScore W1982749890C170033053 @default.
• W1982749890 hasConceptScore W1982749890C170493617 @default.
• W1982749890 hasConceptScore W1982749890C185592680 @default.
• W1982749890 hasConceptScore W1982749890C2776033226 @default.
• W1982749890 hasConceptScore W1982749890C2779627488 @default.
• W1982749890 hasConceptScore W1982749890C519063684 @default.
• W1982749890 hasConceptScore W1982749890C673006 @default.
• W1982749890 hasConceptScore W1982749890C71315377 @default.
• W1982749890 hasConceptScore W1982749890C71924100 @default.

• next