Matches in SemOpenAlex for { <https://semopenalex.org/work/W1982768930> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W1982768930 endingPage "985" @default.
- W1982768930 startingPage "981" @default.
- W1982768930 abstract "Immunosuppressive drugs are usually used in the treatment of acquired aplastic anemia (AAA). The aim of this study was to evaluate the efficiency of a prospective therapeutic protocol using cyclosporine and androgens in the treatment of adult patients with nonsevere AAA.Twenty-nine patients diagnosed and treated at the University Hospital of Sfax (Tunisia), during a 10-year period (1991-2000) were included. In addition to symptomatic treatment (transfusion, antibiotics), all the patients received a specific treatment including two drugs: cyclosporine 5mg/kg per day and androgens 0,5mg/kg per day.The response rate at three, six and 12 months were 48, 75, and 87%, respectively. Survival rate was 52% at one year, and 37% at five and 10 years. The main toxicities were hepatic, renal, and hypertension, observed in 53, 16 and 15%, respectively. These toxicities were reversible in 65, 87 and 100% of the cases, respectively.The response and survival rates in our series are quite satisfactory when compared to those obtained with other immunosuppressive drugs (cyclosporine and antilymphocyte serum) in the literature. The addition of androgens in our patients seemed to potentiate the immunosuppression induced by ciclosporin, but secondary toxic effects were more common." @default.
- W1982768930 created "2016-06-24" @default.
- W1982768930 creator A5000877206 @default.
- W1982768930 creator A5051956051 @default.
- W1982768930 creator A5059102410 @default.
- W1982768930 creator A5065737087 @default.
- W1982768930 creator A5067377366 @default.
- W1982768930 creator A5073822691 @default.
- W1982768930 creator A5073836291 @default.
- W1982768930 creator A5088075013 @default.
- W1982768930 date "2008-12-01" @default.
- W1982768930 modified "2023-10-18" @default.
- W1982768930 title "Évaluation d’un protocole thérapeutique prospectif des aplasies médullaires acquises non sévères de l’adulte dans le Sud tunisien" @default.
- W1982768930 cites W1502200885 @default.
- W1982768930 cites W1918967326 @default.
- W1982768930 cites W1923634318 @default.
- W1982768930 cites W1970972261 @default.
- W1982768930 cites W1991666216 @default.
- W1982768930 cites W1995963264 @default.
- W1982768930 cites W2003132445 @default.
- W1982768930 cites W2015884024 @default.
- W1982768930 cites W2022396757 @default.
- W1982768930 cites W2029965924 @default.
- W1982768930 cites W2036245297 @default.
- W1982768930 cites W2041975887 @default.
- W1982768930 cites W2095496280 @default.
- W1982768930 cites W2106561898 @default.
- W1982768930 cites W2186880799 @default.
- W1982768930 cites W2282248646 @default.
- W1982768930 cites W2341016096 @default.
- W1982768930 cites W2404073832 @default.
- W1982768930 cites W2411656428 @default.
- W1982768930 cites W3134477994 @default.
- W1982768930 cites W43300615 @default.
- W1982768930 cites W2400819172 @default.
- W1982768930 doi "https://doi.org/10.1016/j.revmed.2008.04.006" @default.
- W1982768930 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18502543" @default.
- W1982768930 hasPublicationYear "2008" @default.
- W1982768930 type Work @default.
- W1982768930 sameAs 1982768930 @default.
- W1982768930 citedByCount "0" @default.
- W1982768930 crossrefType "journal-article" @default.
- W1982768930 hasAuthorship W1982768930A5000877206 @default.
- W1982768930 hasAuthorship W1982768930A5051956051 @default.
- W1982768930 hasAuthorship W1982768930A5059102410 @default.
- W1982768930 hasAuthorship W1982768930A5065737087 @default.
- W1982768930 hasAuthorship W1982768930A5067377366 @default.
- W1982768930 hasAuthorship W1982768930A5073822691 @default.
- W1982768930 hasAuthorship W1982768930A5073836291 @default.
- W1982768930 hasAuthorship W1982768930A5088075013 @default.
- W1982768930 hasConcept C126322002 @default.
- W1982768930 hasConcept C2779528694 @default.
- W1982768930 hasConcept C2780252810 @default.
- W1982768930 hasConcept C2911091166 @default.
- W1982768930 hasConcept C29456083 @default.
- W1982768930 hasConcept C71924100 @default.
- W1982768930 hasConcept C90924648 @default.
- W1982768930 hasConceptScore W1982768930C126322002 @default.
- W1982768930 hasConceptScore W1982768930C2779528694 @default.
- W1982768930 hasConceptScore W1982768930C2780252810 @default.
- W1982768930 hasConceptScore W1982768930C2911091166 @default.
- W1982768930 hasConceptScore W1982768930C29456083 @default.
- W1982768930 hasConceptScore W1982768930C71924100 @default.
- W1982768930 hasConceptScore W1982768930C90924648 @default.
- W1982768930 hasIssue "12" @default.
- W1982768930 hasLocation W19827689301 @default.
- W1982768930 hasLocation W19827689302 @default.
- W1982768930 hasOpenAccess W1982768930 @default.
- W1982768930 hasPrimaryLocation W19827689301 @default.
- W1982768930 hasRelatedWork W1999344589 @default.
- W1982768930 hasRelatedWork W2014008695 @default.
- W1982768930 hasRelatedWork W2014193676 @default.
- W1982768930 hasRelatedWork W2033348716 @default.
- W1982768930 hasRelatedWork W2211190999 @default.
- W1982768930 hasRelatedWork W2325673184 @default.
- W1982768930 hasRelatedWork W2403268591 @default.
- W1982768930 hasRelatedWork W2418231793 @default.
- W1982768930 hasRelatedWork W2789448498 @default.
- W1982768930 hasRelatedWork W4306661815 @default.
- W1982768930 hasVolume "29" @default.
- W1982768930 isParatext "false" @default.
- W1982768930 isRetracted "false" @default.
- W1982768930 magId "1982768930" @default.
- W1982768930 workType "article" @default.