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• W1982784674 abstract "The antiproliferative effect of serotonin-reuptake inhibitors (SSRI) and serotonin antagonists has been demonstrated in prostate tumors. Since Hypericum perforatum components act as serotonin-reuptake inhibitors and exert cytotoxic effects on several human cancer cell lines, in this work we analyzed the effect of a treatment with Hypericum perforatum extract (HPE) on the growth of human prostate cancer cells in vitro and in vivo. This study highlighted a significant reduction of tumor growth and number of metastasis suggesting that this natural compound may be useful in the treatment of prostate cancer." @default.
• W1982784674 created "2016-06-24" @default.
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• W1982784674 date "2004-07-01" @default.
• W1982784674 modified "2023-10-01" @default.
• W1982784674 title "Hypericum perforatum methanolic extract inhibits growth of human prostatic carcinoma cell line orthotopically implanted in nude mice" @default.
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• W1982784674 doi "https://doi.org/10.1016/j.canlet.2004.01.031" @default.
• W1982784674 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15172117" @default.
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