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- W1982896645 abstract "Background: Sentinel node (SLN) status is the most important prognostic factor for early-stage melanoma patients. It will influence follow-up and may change therapy. Positive SLNs present different degrees of involvement so that subgroups of patients may have minimal SLN invasion. The aim of this study was to evaluate survival in subgroups with minimally involved SLNs and to compare them to negative SLN patients. Method: SLN biopsy was performed in 499 consecutive clinically N0 patients between 1997 and 2008. Following updated recommendations from the Melanoma Group of the European Organization of Research and Treatment of Cancer, degrees of SLN involvement were fully reassessed for two anatomopathological parameters: tumour burden according to Rotterdam criteria (1.0 mm) and microanatomic location according to Dewar (subcapsular, combined subcapsular and parenchymal, parenchymal, multifocal, or extensive). Minimally involved SLNs were defined as those with tumor burden" @default.
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- W1982896645 date "2013-01-01" @default.
- W1982896645 modified "2023-09-29" @default.
- W1982896645 title "The Prognostic Value of Minimally Involved Melanoma Sentinel Lymph Nodes" @default.
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- W1982896645 doi "https://doi.org/10.4236/jct.2013.410180" @default.
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