FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1982900536> ?p ?o ?g. }

• W1982900536 endingPage "682" @default.
• W1982900536 startingPage "673" @default.
• W1982900536 abstract "Structure–activity profiles for the phytohormone auxin have been collected for over 70 years, and a number of synthetic auxins are used in agriculture. Auxin classification schemes and binding models followed from understanding auxin structures. However, all of the data came from whole plant bioassays, meaning the output was the integral of many different processes. The discovery of Transport Inhibitor-Response 1 (TIR1) and the Auxin F-Box (AFB) proteins as sites of auxin perception and the role of auxin as molecular glue in the assembly of co-receptor complexes has allowed the development of a definitive quantitative structure–activity relationship for TIR1 and AFB5. Factorial analysis of binding activities offered two uncorrelated factors associated with binding efficiency and binding selectivity. The six maximum-likelihood estimators of Efficiency are changes in the overlap matrixes, inferring that Efficiency is related to the volume of the electronic system. Using the subset of compounds that bound strongly, chemometric analyses based on quantum chemical calculations and similarity and self-similarity indices yielded three classes of Specificity that relate to differential binding. Specificity may not be defined by any one specific atom or position and is influenced by coulomb matrixes, suggesting that it is driven by electrostatic forces. These analyses give the first receptor-specific classification of auxins and indicate that AFB5 is the preferred site for a number of auxinic herbicides by allowing interactions with analogues having van der Waals surfaces larger than that of indole-3-acetic acid. The quality factors are also examined in terms of long-standing models for the mechanism of auxin binding." @default.
• W1982900536 created "2016-06-24" @default.
• W1982900536 creator A5006550776 @default.
• W1982900536 creator A5011105812 @default.
• W1982900536 creator A5034255344 @default.
• W1982900536 creator A5041627667 @default.
• W1982900536 creator A5053790185 @default.
• W1982900536 creator A5063272319 @default.
• W1982900536 creator A5076789861 @default.
• W1982900536 creator A5086903537 @default.
• W1982900536 date "2013-12-23" @default.
• W1982900536 modified "2023-10-16" @default.
• W1982900536 title "Defining Binding Efficiency and Specificity of Auxins for SCF^TIR1/AFB-Aux/IAA Co-receptor Complex Formation" @default.
• W1982900536 cites W1524878541 @default.
• W1982900536 cites W1568611842 @default.
• W1982900536 cites W1972633502 @default.
• W1982900536 cites W1972893469 @default.
• W1982900536 cites W1978489676 @default.
• W1982900536 cites W1990621581 @default.
• W1982900536 cites W2010981101 @default.
• W1982900536 cites W2012946860 @default.
• W1982900536 cites W2028204660 @default.
• W1982900536 cites W2031199055 @default.
• W1982900536 cites W2035443430 @default.
• W1982900536 cites W2049054284 @default.
• W1982900536 cites W2049656920 @default.
• W1982900536 cites W2059326685 @default.
• W1982900536 cites W2065120230 @default.
• W1982900536 cites W2067478074 @default.
• W1982900536 cites W2076228503 @default.
• W1982900536 cites W2087997250 @default.
• W1982900536 cites W2109446031 @default.
• W1982900536 cites W2110909424 @default.
• W1982900536 cites W2114990930 @default.
• W1982900536 cites W2123490201 @default.
• W1982900536 cites W2132274675 @default.
• W1982900536 cites W2132927838 @default.
• W1982900536 cites W2134341756 @default.
• W1982900536 cites W2138589440 @default.
• W1982900536 cites W2141656509 @default.
• W1982900536 cites W2143827494 @default.
• W1982900536 cites W2152123775 @default.
• W1982900536 cites W2160648204 @default.
• W1982900536 cites W2162373838 @default.
• W1982900536 cites W2172700797 @default.
• W1982900536 doi "https://doi.org/10.1021/cb400618m" @default.
• W1982900536 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3964829" @default.
• W1982900536 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24313839" @default.
• W1982900536 hasPublicationYear "2013" @default.
• W1982900536 type Work @default.
• W1982900536 sameAs 1982900536 @default.
• W1982900536 citedByCount "88" @default.
• W1982900536 countsByYear W19829005362014 @default.
• W1982900536 countsByYear W19829005362015 @default.
• W1982900536 countsByYear W19829005362016 @default.
• W1982900536 countsByYear W19829005362017 @default.
• W1982900536 countsByYear W19829005362018 @default.
• W1982900536 countsByYear W19829005362019 @default.
• W1982900536 countsByYear W19829005362020 @default.
• W1982900536 countsByYear W19829005362021 @default.
• W1982900536 countsByYear W19829005362022 @default.
• W1982900536 countsByYear W19829005362023 @default.
• W1982900536 crossrefType "journal-article" @default.
• W1982900536 hasAuthorship W1982900536A5006550776 @default.
• W1982900536 hasAuthorship W1982900536A5011105812 @default.
• W1982900536 hasAuthorship W1982900536A5034255344 @default.
• W1982900536 hasAuthorship W1982900536A5041627667 @default.
• W1982900536 hasAuthorship W1982900536A5053790185 @default.
• W1982900536 hasAuthorship W1982900536A5063272319 @default.
• W1982900536 hasAuthorship W1982900536A5076789861 @default.
• W1982900536 hasAuthorship W1982900536A5086903537 @default.
• W1982900536 hasBestOaLocation W19829005361 @default.
• W1982900536 hasConcept C104317684 @default.
• W1982900536 hasConcept C107824862 @default.
• W1982900536 hasConcept C12554922 @default.
• W1982900536 hasConcept C185592680 @default.
• W1982900536 hasConcept C207778908 @default.
• W1982900536 hasConcept C55493867 @default.
• W1982900536 hasConcept C71240020 @default.
• W1982900536 hasConcept C86803240 @default.
• W1982900536 hasConceptScore W1982900536C104317684 @default.
• W1982900536 hasConceptScore W1982900536C107824862 @default.
• W1982900536 hasConceptScore W1982900536C12554922 @default.
• W1982900536 hasConceptScore W1982900536C185592680 @default.
• W1982900536 hasConceptScore W1982900536C207778908 @default.
• W1982900536 hasConceptScore W1982900536C55493867 @default.
• W1982900536 hasConceptScore W1982900536C71240020 @default.
• W1982900536 hasConceptScore W1982900536C86803240 @default.
• W1982900536 hasIssue "3" @default.
• W1982900536 hasLocation W19829005361 @default.
• W1982900536 hasLocation W19829005362 @default.
• W1982900536 hasLocation W19829005363 @default.
• W1982900536 hasLocation W19829005364 @default.
• W1982900536 hasLocation W19829005365 @default.
• W1982900536 hasOpenAccess W1982900536 @default.
• W1982900536 hasPrimaryLocation W19829005361 @default.
• W1982900536 hasRelatedWork W1976272641 @default.
• W1982900536 hasRelatedWork W2004073475 @default.

• next