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• W1982945551 abstract "<i>Purpose:</i> We investigated the effects of various rinsing and healing protocols on corneal wound repair and inflammation following alkali burn in rabbits. <i>Methods:</i> We conducted in vitro, in vivo and ex vivo studies. First, different rinse solutions were tested in vitro after incubation of ocular cells with methanol or NaOH. Cell viability was then assessed using the neutral red test (cytofluorometry). Second, NaOH was applied to rabbit corneas and associations of rinse solutions (NaCl 0.9% or controlled ionization marine solutions) with N-acetylcysteine or vegetable oils (from <i>Calophyllum inophyllum </i>and <i>Aleurites moluccana</i>) were tested in vivo. The regeneration of the corneal epithelium and the infiltration of inflammatory cells were evaluated using in vivo confocal microscopy and ex vivo histological cuts. <i>Results:</i> The association of a controlled ionization marine solution with 10%<i> C. inophyllum </i>oil and 90% <i>A. moluccana</i> oil induced regeneration of the corneal epithelium and a decrease in inflammatory cells. <i>Conclusions:</i> Irrigation with marine solution followed by treatment with a mixture of <i>C. inophyllum</i> and <i>A. moluccana</i> oils is a promising treatment for ocular burns." @default.
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• W1982945551 date "2008-11-20" @default.
• W1982945551 modified "2023-10-01" @default.
• W1982945551 title "Ocular Burn: Rinsing and Healing with Ionic Marine Solutions and Vegetable Oils" @default.
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• W1982945551 doi "https://doi.org/10.1159/000172618" @default.
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