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- W1982955122 abstract "A detector for use in the control of isoniazid treatment is described. It detects the urinary metabolites of isoniazid, isonicotinic acid and isonicotinyl glycine, at concentrations of 4μg.g. per ml. or more. It is based on the reaction of cyanogen chloride and barbituric acid with these compounds. Clinical studies revealed that 2 hrs. after 100 mg. of isoniazid orally 17 out of 18 tested specimens of urine were positive. In the interval 4 to 24 hrs. after the same dose all specimens were positive. After an oral dose of 200 mg. isoniazid all 9 tested urine specimens were positive within 1 to 24 hrs. after administration of the drug." @default.
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- W1982955122 date "1961-01-01" @default.
- W1982955122 modified "2023-10-17" @default.
- W1982955122 title "A new urine test for the control of isoniazid therapy" @default.
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- W1982955122 doi "https://doi.org/10.1016/s0041-3879(61)80143-8" @default.
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