Matches in SemOpenAlex for { <https://semopenalex.org/work/W1983146118> ?p ?o ?g. }
- W1983146118 endingPage "288" @default.
- W1983146118 startingPage "281" @default.
- W1983146118 abstract "Abstract: Mercury (Hg) exposure causes health problems that may result from increased oxidative stress and matrix metalloproteinase (MMP) levels. We investigated whether there is an association between the circulating levels of MMP‐2, MMP‐9, their endogenous inhibitors (the tissue inhibitors of metalloproteinases; TIMPs) and the circulating Hg levels in 159 subjects environmentally exposed to Hg. Blood and plasma Hg were determined by inductively coupled plasma‐mass spectrometry (ICP‐MS). MMP and TIMP concentrations were measured in plasma samples by gelatin zymography and ELISA respectively. Thiobarbituric acid‐reactive species (TBARS) were measured in plasma to assess oxidative stress. Selenium (Se) levels were determined by ICP‐MS because it is an antioxidant. The relations between bioindicators of Hg and the metalloproteinases levels were examined using multivariate regression models. While we found no relation between blood or plasma Hg and MMP‐9, plasma Hg levels were negatively associated with TIMP‐1 and TIMP‐2 levels, and thereby with increasing MMP‐9/TIMP‐1 and MMP‐2/TIMP‐2 ratios, thus indicating a positive association between plasma Hg and circulating net MMP‐9 and MMP‐2 activities. These findings provide a new insight into the possible biological mechanisms of Hg toxicity, particularly in cardiovascular diseases." @default.
- W1983146118 created "2016-06-24" @default.
- W1983146118 creator A5002216895 @default.
- W1983146118 creator A5022834761 @default.
- W1983146118 creator A5023820741 @default.
- W1983146118 creator A5061239800 @default.
- W1983146118 creator A5064992089 @default.
- W1983146118 creator A5067971882 @default.
- W1983146118 creator A5068248835 @default.
- W1983146118 creator A5079869767 @default.
- W1983146118 creator A5086159135 @default.
- W1983146118 date "2009-09-11" @default.
- W1983146118 modified "2023-10-17" @default.
- W1983146118 title "Mercury Exposure Increases Circulating Net Matrix Metalloproteinase (MMP)-2 and MMP-9 Activities" @default.
- W1983146118 cites W1553653105 @default.
- W1983146118 cites W1590457525 @default.
- W1983146118 cites W1649452503 @default.
- W1983146118 cites W1785518762 @default.
- W1983146118 cites W1785699085 @default.
- W1983146118 cites W1966993197 @default.
- W1983146118 cites W1967808502 @default.
- W1983146118 cites W1968890334 @default.
- W1983146118 cites W1971515408 @default.
- W1983146118 cites W1973858712 @default.
- W1983146118 cites W1975723842 @default.
- W1983146118 cites W1977240310 @default.
- W1983146118 cites W1982728245 @default.
- W1983146118 cites W1986316446 @default.
- W1983146118 cites W1989070719 @default.
- W1983146118 cites W1997680731 @default.
- W1983146118 cites W2014933300 @default.
- W1983146118 cites W2018574106 @default.
- W1983146118 cites W2025534134 @default.
- W1983146118 cites W2025559497 @default.
- W1983146118 cites W2025785991 @default.
- W1983146118 cites W2026803942 @default.
- W1983146118 cites W2040330912 @default.
- W1983146118 cites W2047081377 @default.
- W1983146118 cites W2049002475 @default.
- W1983146118 cites W2050290821 @default.
- W1983146118 cites W2064755830 @default.
- W1983146118 cites W2068982039 @default.
- W1983146118 cites W2071448071 @default.
- W1983146118 cites W2072170658 @default.
- W1983146118 cites W2072249256 @default.
- W1983146118 cites W2072542797 @default.
- W1983146118 cites W2072553979 @default.
- W1983146118 cites W2073259535 @default.
- W1983146118 cites W2074988581 @default.
- W1983146118 cites W2077164861 @default.
- W1983146118 cites W2093979559 @default.
- W1983146118 cites W2095250290 @default.
- W1983146118 cites W2100333367 @default.
- W1983146118 cites W2105159315 @default.
- W1983146118 cites W2106629880 @default.
- W1983146118 cites W2106834148 @default.
- W1983146118 cites W2130445180 @default.
- W1983146118 cites W2140828836 @default.
- W1983146118 cites W2141611253 @default.
- W1983146118 cites W2147921761 @default.
- W1983146118 cites W2152692075 @default.
- W1983146118 cites W2166066712 @default.
- W1983146118 cites W2166608740 @default.
- W1983146118 cites W2166625580 @default.
- W1983146118 cites W2167280136 @default.
- W1983146118 cites W2168649322 @default.
- W1983146118 cites W4210999932 @default.
- W1983146118 cites W4255745174 @default.
- W1983146118 cites W4256460995 @default.
- W1983146118 doi "https://doi.org/10.1111/j.1742-7843.2009.00443.x" @default.
- W1983146118 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19594729" @default.
- W1983146118 hasPublicationYear "2009" @default.
- W1983146118 type Work @default.
- W1983146118 sameAs 1983146118 @default.
- W1983146118 citedByCount "18" @default.
- W1983146118 countsByYear W19831461182012 @default.
- W1983146118 countsByYear W19831461182015 @default.
- W1983146118 countsByYear W19831461182016 @default.
- W1983146118 countsByYear W19831461182017 @default.
- W1983146118 countsByYear W19831461182019 @default.
- W1983146118 countsByYear W19831461182021 @default.
- W1983146118 crossrefType "journal-article" @default.
- W1983146118 hasAuthorship W1983146118A5002216895 @default.
- W1983146118 hasAuthorship W1983146118A5022834761 @default.
- W1983146118 hasAuthorship W1983146118A5023820741 @default.
- W1983146118 hasAuthorship W1983146118A5061239800 @default.
- W1983146118 hasAuthorship W1983146118A5064992089 @default.
- W1983146118 hasAuthorship W1983146118A5067971882 @default.
- W1983146118 hasAuthorship W1983146118A5068248835 @default.
- W1983146118 hasAuthorship W1983146118A5079869767 @default.
- W1983146118 hasAuthorship W1983146118A5086159135 @default.
- W1983146118 hasConcept C109523444 @default.
- W1983146118 hasConcept C126322002 @default.
- W1983146118 hasConcept C134018914 @default.
- W1983146118 hasConcept C162356407 @default.
- W1983146118 hasConcept C165697059 @default.
- W1983146118 hasConcept C177430391 @default.
- W1983146118 hasConcept C185592680 @default.